Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 5/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALPG | P10696 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8044240 | 0.86 | KMT2A (0.35) | KMT2AALDH1A1MAPTPSMD14HTT | |
| SCHEMBL8045604 | 0.82 | ALDH1A1 (0.34) | KMT2AALDH1A1MAPTHTTSMN1; SMN2 | |
| SCHEMBL8043929 | 0.81 | MAPK8 (0.47) | KMT2AALDH1A1MAPTPSMD14HTT | |
| SCHEMBL8042232 | 0.81 | ALDH1A1 (0.50) | KMT2AALDH1A1MAPTHTTGAA | |
| SCHEMBL8045769 | 0.80 | ALDH1A1 (0.36) | KMT2AALDH1A1MAPTHTTGAA | |
| SCHEMBL8047853 | 0.80 | KMT2A (0.40) | KMT2AALDH1A1MAPTPSMD14HTT | |
| SCHEMBL8042606 | 0.79 | ALDH1A1 (0.37) | KMT2AALDH1A1MAPTPSMD14HTT | |
| SCHEMBL8044826 | 0.78 | PDK1 (0.53) | KMT2AALDH1A1MAPTHTTGAA | |
| SCHEMBL8046591 | 0.78 | ALDH1A1 (0.39) | KMT2AALDH1A1MAPTPSMD14HTT | |
| SCHEMBL8043070 | 0.77 | ALDH1A1 (0.41) | KMT2AALDH1A1MAPTHTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |