Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 16/20 | 0.50 |
| ▸ | PPARG | P37231 | 6/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.40 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8039541 | 0.95 | PPARA (0.49) | PPARAPPARGTTRCYP1A2CYP2C8 | |
| SCHEMBL8617696 | 0.91 | PPARA (0.54) | PPARAPPARGTTRCYP1A2CYP2C8 | |
| SCHEMBL8620438 | 0.89 | PPARA (0.48) | PPARAPPARGTTRCYP1A2CYP2C8 | |
| SCHEMBL8617485 | 0.88 | PPARA (0.37) | PPARAPPARGTDP1CYP4F2CYP4A11 | |
| SCHEMBL8624144 | 0.86 | PPARA (0.54) | PPARAPPARGTTRCYP1A2CYP2C8 | |
| SCHEMBL8619033 | 0.86 | PPARA (0.54) | PPARAPPARGPPARD | |
| SCHEMBL8052016 | 0.82 | PPARA (0.60) | PPARAPPARGTTRCYP1A2CYP2C8 | |
| SCHEMBL8768773 | 0.82 | PPARA (0.54) | PPARAPPARGPPARD | |
| SCHEMBL8767430 | 0.78 | PPARA (0.56) | PPARAPPARGPPARD | |
| SCHEMBL9068527 | 0.78 | ELANE (0.45) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0763527-B1 | Substituted 2,2-dimethyl-omega-phenoxy alkanoic acids and esters, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-04-26 | — | — | EP | claimed |
| US-5734077-A | ANTILIPEMIC AGENTS, ANTICHOLESTEROL AGENTS, TREATMENT OF DIABETES AND ATHEROSCLEROSIS | ADIR ET COMPAGNIE (FR) | 1998-03-31 | — | — | US | claimed |
| JP-9132547-A | — | — | None | — | — | JP | disclosed |
| EP-0763527-B1 | Substituted 2,2-dimethyl-omega-phenoxy alkanoic acids and esters, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-04-26 | — | — | EP | disclosed |
| US-5734077-A | ANTILIPEMIC AGENTS, ANTICHOLESTEROL AGENTS, TREATMENT OF DIABETES AND ATHEROSCLEROSIS | ADIR ET COMPAGNIE (FR) | 1998-03-31 | — | — | US | disclosed |
| JP-H09132547-A | SUBSTITUTED 2, 2-DIMETHYL-OMEGA-PHENOXYALKANOIC ACID, ITS ESTER, THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | ADIR | 1997-05-20 | — | — | JP | disclosed |
| EP-0763527-A1 | Substituted 2,2-dimethyl-omega-phenoxy alkanoic acids and esters, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-03-19 | — | — | EP | disclosed |