SCHEMBL8619033

SCHEMBL8619033

CC(C)(CCCOc1ccc(CCOc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)cc1)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 19/20 0.54
PPARD Q03181 8/20 0.46
PPARG P37231 4/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8624144 0.95 PPARA (0.54) PPARAPPARG
SCHEMBL8052016 0.91 PPARA (0.60) PPARAPPARG
SCHEMBL8049917 0.87 PPARA (0.51) PPARAPPARG
SCHEMBL8049899 0.86 PPARA (0.50) PPARAPPARDPPARG
SCHEMBL8039541 0.85 PPARA (0.49) PPARAPPARDPPARG
SCHEMBL8924029 0.83 PPARG (0.64) PPARAPPARDPPARG
SCHEMBL8617696 0.81 PPARA (0.54) PPARAPPARG
SCHEMBL8616686 0.80 PPARA (0.51) PPARAPPARDPPARG
SCHEMBL8050263 0.79 PPARA (0.65) PPARAPPARG
SCHEMBL11097170 0.79 PPARA (0.81) PPARAPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5734077-A ANTILIPEMIC AGENTS, ANTICHOLESTEROL AGENTS, TREATMENT OF DIABETES AND ATHEROSCLEROSIS ADIR ET COMPAGNIE (FR) 1998-03-31 US disclosed