Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 7/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8049899 | 0.88 | PPARA (0.50) | PPARAS1PR1S1PR4S1PR3S1PR5 | |
| SCHEMBL8039541 | 0.82 | PPARA (0.49) | PPARACYP4F2CYP4A11PPARGTDP1 | |
| SCHEMBL8617696 | 0.79 | PPARA (0.54) | PPARACYP4F2CYP4A11PPARGTDP1 | |
| SCHEMBL8617055 | 0.78 | CYP4F2 (0.52) | PPARAS1PR1S1PR4S1PR3S1PR5 | |
| SCHEMBL8620438 | 0.78 | PPARA (0.48) | PPARACYP4F2CYP4A11PPARGTDP1 | |
| SCHEMBL10459179 | 0.77 | S1PR1 (0.46) | PPARAS1PR1S1PR4S1PR3S1PR5 | |
| SCHEMBL8624692 | 0.77 | PPARA (0.45) | PPARAS1PR1S1PR4S1PR3S1PR5 | |
| SCHEMBL9042925 | 0.75 | HRH2 (0.37) | TDP1L3MBTL1 | |
| SCHEMBL8619033 | 0.74 | PPARA (0.54) | PPARAPPARG | |
| SCHEMBL8768773 | 0.74 | PPARA (0.54) | PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5734077-A | ANTILIPEMIC AGENTS, ANTICHOLESTEROL AGENTS, TREATMENT OF DIABETES AND ATHEROSCLEROSIS | ADIR ET COMPAGNIE (FR) | 1998-03-31 | — | — | US | disclosed |