Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 4/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | CES2 | O00748 | 4/20 | 0.45 |
| ▸ | CES1 | P23141 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11855491 | 0.81 | TDP1 (0.48) | TDP1L3MBTL1ATMHSP90AA1GAA | |
| SCHEMBL27618402 | 0.80 | TDP1 (0.44) | TDP1L3MBTL1ATMHSP90AA1GAA | |
| SCHEMBL5205446 | 0.80 | PARP1 (0.50) | TDP1ATMKCNH2MEN1KMT2A | |
| SCHEMBL9772285 | 0.78 | ALKBH5 (0.60) | TDP1L3MBTL1ATMNPC1RAB9A | |
| SCHEMBL10776096 | 0.77 | PGR (0.48) | TDP1L3MBTL1ATMNPC1RAB9A | |
| SCHEMBL2329814 | 0.76 | ATM (0.55) | TDP1L3MBTL1ATMHSP90AA1GAA | |
| SCHEMBL10716596 | 0.76 | ATM (0.55) | TDP1L3MBTL1ATMHSP90AA1GAA | |
| SCHEMBL7809333 | 0.75 | ALKBH5 (0.47) | TDP1L3MBTL1ATMNPC1RAB9A | |
| SCHEMBL5031717 | 0.75 | TDP1 (0.47) | TDP1L3MBTL1ATMNPC1RAB9A | |
| SCHEMBL2238176 | 0.75 | TDP1 (0.56) | TDP1L3MBTL1ATMHSP90AA1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798294-B1 | Process for preparing alpha-haloacetophenone derivative | SUMITOMO SEIKA CHEMICALS (JP) | 2000-06-14 | — | — | EP | disclosed |
| US-5821388-A | Process for preparing α-haloacetophenone derivative | SUMITOMO SEIKA CHEMICAL CO., LTD. (JP) | 1998-10-13 | — | — | US | disclosed |
| EP-0798294-A2 | Process for preparing haloacetophenone derivative | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1997-10-01 | — | — | EP | disclosed |