Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 5/20 | 0.45 |
| ▸ | CES2 | O00748 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9772285 | 0.78 | ALKBH5 (0.60) | ALKBH5TDP1L3MBTL1CES1CES2 | |
| SCHEMBL10776096 | 0.77 | PGR (0.48) | ALKBH5TDP1L3MBTL1CES1CES2 | |
| SCHEMBL2073695 | 0.76 | TDP1 (0.52) | ALKBH5TDP1L3MBTL1CES1CES2 | |
| SCHEMBL15450052 | 0.75 | MAPT (0.53) | ALKBH5TDP1L3MBTL1CES1CES2 | |
| SCHEMBL5031717 | 0.75 | TDP1 (0.47) | ALKBH5TDP1L3MBTL1CES1CES2 | |
| SCHEMBL8050145 | 0.75 | TDP1 (0.47) | ALKBH5TDP1L3MBTL1CES1CES2 | |
| SCHEMBL1548851 | 0.75 | TDP1 (0.56) | ALKBH5TDP1L3MBTL1CES1CES2 | |
| SCHEMBL1492635 | 0.75 | CES1 (0.57) | ALKBH5TDP1L3MBTL1CES1CES2 | |
| SCHEMBL8804842 | 0.73 | L3MBTL1 (0.55) | ALKBH5TDP1L3MBTL1CES1CES2 | |
| SCHEMBL2379357 | 0.73 | CES1 (0.58) | ALKBH5TDP1L3MBTL1CES1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780380-B1 | Triazole derivatives with antimycotic action and intermediates | SS PHARMACEUTICAL CO (JP) | 2001-06-13 | — | — | EP | disclosed |
| US-6002028-A | FUNGICIDES | SS PHARMACEUTICAL CO., LTD. (JP) | 1999-12-14 | — | — | US | disclosed |
| US-5986144-A | Triazole derivative, preparation process thereof and pharmaceutical comprising the same as an effective ingredient | SS PHARMACEUTICAL CO., LTD. (JP) | 1999-11-16 | — | — | US | disclosed |
| US-5945438-A | ANTIMYCOTIC AGENT | SS PHARMACEUTICAL CO., LTD. (JP) | 1999-08-31 | — | — | US | disclosed |
| EP-0780380-A1 | Triazole derivatives with antimycotic action and intermediates | SS PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | disclosed |