SCHEMBL8050211

SCHEMBL8050211

CCCCCCCCCOC(=O)C(c1ccccc1O)C1CCCC1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.47
TSHR P16473 3/20 0.47
LMNA P02545 2/20 0.47
CHRM2 P08172 1/20 0.47
HTR1A P08908 1/20 0.47
ADRA2A P08913 1/20 0.47
CHRM1 P11229 1/20 0.47
DRD1 P21728 1/20 0.47
SLC6A2 P23975 1/20 0.47
ADRA1A P35348 1/20 0.47
OPRM1 P35372 1/20 0.47
DRD3 P35462 1/20 0.47
SLC6A3 Q01959 1/20 0.47
KCNH2 Q12809 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2D6 P10635 1/20 0.47
CHRM3 P20309 1/20 0.45
ALDH1A1 P00352 1/20 0.45
TP53 P04637 1/20 0.43
MAPK1 P28482 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28637337 0.84 SLC6A2 (0.66) CYP3A4TSHRLMNACHRM2HTR1A
SCHEMBL28619401 0.84 SLC6A2 (0.66) CYP3A4TSHRLMNACHRM2HTR1A
SCHEMBL28636471 0.84 SLC6A2 (0.66) CYP3A4TSHRLMNACHRM2HTR1A
SCHEMBL6951792 0.83 TSHR (0.51) CYP3A4TSHRLMNACHRM2HTR1A
SCHEMBL28622638 0.82 SLC6A3 (0.67) CYP3A4TSHRLMNACHRM2HTR1A
SCHEMBL5400537 0.79 SLC6A3 (0.51) SLC6A2SLC6A3
SCHEMBL28622583 0.78 SLC6A2 (0.69) CYP3A4TSHRLMNACHRM2HTR1A
SCHEMBL5379375 0.78 SLC6A3 (0.52) SLC6A2SLC6A3
SCHEMBL2728744 0.78 TSHR (0.53) CYP3A4TSHRLMNAALDH1A1TP53
SCHEMBL5668367 0.76 TSHR (0.51) CYP3A4TSHRLMNAALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6028198-A CATALYTIC ESTERIFICATION OF 3-METHYL AZABICYCLO (3, 3, 1) NONAN-9 ALPHA-OL WITH METHYL OR ETHYL 2-PHENYL-2-CYCLOPENTYL-2-HYDROXY-ACETATE OR 2-PHENYL-2-CYCLOPENTYL-2-HYDROXY-ACETIC ACID INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY SCIENCES P.L.A. (CN) 2000-02-22 US disclosed