SCHEMBL28636471

SCHEMBL28636471

CCCCCCCOC(=O)C(c1ccccc1)C1CCCC1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 4/20 0.66
SLC6A3 Q01959 4/20 0.66
LMNA P02545 4/20 0.66
CYP3A4 P08684 2/20 0.66
TSHR P16473 2/20 0.66
CHRM2 P08172 1/20 0.66
HTR1A P08908 1/20 0.66
ADRA2A P08913 1/20 0.66
CHRM1 P11229 1/20 0.66
DRD1 P21728 1/20 0.66
ADRA1A P35348 1/20 0.66
OPRM1 P35372 1/20 0.66
DRD3 P35462 1/20 0.66
KCNH2 Q12809 1/20 0.66
CYP1A2 P05177 1/20 0.66
CYP2D6 P10635 1/20 0.66
CHRM3 P20309 2/20 0.59
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28619401 1.00 SLC6A2 (0.66) SLC6A2SLC6A3LMNACYP3A4TSHR
SCHEMBL28637337 1.00 SLC6A2 (0.66) SLC6A2SLC6A3LMNACYP3A4TSHR
SCHEMBL28622638 0.99 SLC6A3 (0.67) SLC6A2SLC6A3LMNACYP3A4TSHR
SCHEMBL28622583 0.95 SLC6A2 (0.69) SLC6A2SLC6A3LMNACYP3A4TSHR
SCHEMBL7489656 0.86 SLC6A2 (0.68) SLC6A2SLC6A3LMNACYP3A4TSHR
SCHEMBL8050211 0.84 CYP3A4 (0.47) SLC6A2SLC6A3LMNACYP3A4TSHR
SCHEMBL28632940 0.83 SLC6A2 (0.67) SLC6A2SLC6A3LMNACYP3A4TSHR
SCHEMBL28623956 0.81 SLC6A3 (0.65) SLC6A2SLC6A3LMNACYP3A4TSHR
Drofenine SCHEMBL25124 0.80 CHRM2 (1.00) SLC6A2SLC6A3LMNACYP3A4TSHR
Hexasonium SCHEMBL29385478 0.79 SLC6A2 (0.66) SLC6A2SLC6A3LMNACYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109457011-B Method for splitting alpha-cyclopentylphenylacetic acid enantiomer through stereoselective enzymatic hydrolysis 湖南理工学院 2021-09-07 CN disclosed