SCHEMBL8050282

SCHEMBL8050282

NCCCC(=O)NCC(O)CO

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 2/20 0.41
GABRR3 A8MPY1 1/20 0.37
GABRP O00591 1/20 0.37
GABRD O14764 1/20 0.37
HDAC3 O15379 1/20 0.37
GABBR2 O75899 1/20 0.37
LMNA P02545 1/20 0.37
CYP1A2 P05177 1/20 0.37
THRB P10828 1/20 0.37
GABRA1 P14867 1/20 0.37
TSHR P16473 1/20 0.37
GABRB1 P18505 1/20 0.37
GABRG2 P18507 1/20 0.37
GABRR1 P24046 1/20 0.37
GABRB3 P28472 1/20 0.37
GABRR2 P28476 1/20 0.37
SLC6A1 P30531 1/20 0.37
GABRA5 P31644 1/20 0.37
GABRA3 P34903 1/20 0.37
GABRA2 P47869 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8060619 0.93 MMP2 (0.49) MMP2LMNATHRBBLMKMT2A
SCHEMBL31458680 0.93 MMP2 (0.49) MMP2LMNATHRBBLMKMT2A
SCHEMBL890353 0.88 MMP2 (0.45) MMP2LMNATSHRCA2TLR2
SCHEMBL18608295 0.85 PTPN1 (0.37) MMP2TSHRPTPN1CA2ASAH1
SCHEMBL14700212 0.85 PTPN1 (0.37) MMP2TSHRPTPN1CA2ASAH1
SCHEMBL14700211 0.81 PTPN1 (0.44) LMNATSHRPTPN1ASAH1HPGD
SCHEMBL9647324 0.81 PTPN1 (0.37) HDAC3LMNAHDAC4HDAC1HDAC7
SCHEMBL30094413 0.80 KDM4E (0.41) MMP2GABRR3GABRPGABRDHDAC3
SCHEMBL12214348 0.79 NAAA (0.39) LMNATHRBKMT2APTPN1CA2
SCHEMBL12214451 0.79 MMP2 (0.41) MMP2LMNACYP1A2TSHRGABRR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115942939-A Diastereomer ligation reagents for nucleotide probes 布伦塔诺生物技术联合公司 2023-04-07 CN disclosed
WO-2021061154-A1 DIASTEREOMERIC LINKING REAGENTS FOR NUCLEOTIDE PROBES BRENTANO BIOTECHNOLOGY ASSOCIATES (US) 2021-04-01 WO disclosed
US-6031091-A WITH PROTECTING GROUPS WHICH MAY BE REMOVED FOR COUPLING TO ANOTHER NUCLEOTIDE; FOR HYBRIDIZATION PROBES WITH ENHANCED SENSITIVITY GEN-PROBE INCORPORATED (US) 2000-02-29 US disclosed
US-5696251-A OLIGONUCLEOTIDES GEN-PROBE INCORPORATED (US) 1997-12-09 US disclosed
US-5656744-A COMPLEXING GEN-PROBE INCORPORATED (US) 1997-08-12 US disclosed
US-5585481-A VERSATILITY; NON-NUCLEOTIDE MONOMERIC UNIT HAVING A LIGAND AND FIRST AND SECOND COUPLING GROUPS WHICH ARE LINKED TO THE NON-NUCLEOTIDE MONOMERIC UNIT ; LABELS, INTERCALATORS, PROBES GEN-PROBE INCORPORATED (US) 1996-12-17 US disclosed
EP-0313219-B1 Non-nucleotide linking reagents for nucleotide probes GEN PROBE INC (US) 1996-05-08 EP disclosed
WO-1989002439-A1 NON-NUCLEOTIDE LINKING REAGENTS FOR NUCLEOTIDE PROBES ML TECHNOLOGY VENTURES, L.P. (US) 1989-03-23 WO disclosed