SCHEMBL8060619

SCHEMBL8060619

NCCCCCC(=O)NCC(O)CO

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 1/20 0.49
SLC6A5 Q9Y345 2/20 0.42
PTPN1 P18031 1/20 0.41
MEN1 O00255 1/20 0.41
ALDH1A1 P00352 1/20 0.41
PLG P00747 1/20 0.41
LMNA P02545 1/20 0.41
THRB P10828 1/20 0.41
ALOX15 P16050 1/20 0.41
SLC6A2 P23975 1/20 0.41
RECQL P46063 1/20 0.41
SLC6A3 Q01959 1/20 0.41
KMT2A Q03164 1/20 0.41
NMT2 O60551 2/20 0.40
NMT1 P30419 2/20 0.40
PAOX Q6QHF9 3/20 0.39
CYP3A4 P08684 1/20 0.39
ASAH1 Q13510 1/20 0.38
CYP2D6 P10635 1/20 0.38
NFKB1 P19838 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31458680 1.00 MMP2 (0.49) MMP2SLC6A5PTPN1MEN1ALDH1A1
SCHEMBL8050282 0.93 MMP2 (0.41) MMP2SLC6A5PTPN1LMNATHRB
SCHEMBL25557768 0.85 MMP2 (0.44) MMP2SLC6A5PTPN1MEN1ALDH1A1
SCHEMBL890353 0.85 MMP2 (0.45) MMP2ALDH1A1LMNASLC6A2CYP3A4
SCHEMBL24339916 0.82 FAAH (0.58) MEN1LMNAKMT2AASAH1FAAH
SCHEMBL5410583 0.82 FAAH (0.58) MEN1LMNAKMT2AASAH1FAAH
SCHEMBL5058537 0.82 PTPN1 (0.41) PTPN1ASAH1FAAH
SCHEMBL1004187 0.82 FAAH (0.58) MEN1LMNAKMT2AASAH1FAAH
SCHEMBL22067566 0.82 FAAH (0.58) MEN1LMNAKMT2AASAH1FAAH
SCHEMBL12858914 0.82 PTPN1 (0.41) PTPN1ASAH1FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115942939-A Diastereomer ligation reagents for nucleotide probes 布伦塔诺生物技术联合公司 2023-04-07 CN disclosed
WO-2021061154-A1 DIASTEREOMERIC LINKING REAGENTS FOR NUCLEOTIDE PROBES BRENTANO BIOTECHNOLOGY ASSOCIATES (US) 2021-04-01 WO disclosed
US-6031091-A WITH PROTECTING GROUPS WHICH MAY BE REMOVED FOR COUPLING TO ANOTHER NUCLEOTIDE; FOR HYBRIDIZATION PROBES WITH ENHANCED SENSITIVITY GEN-PROBE INCORPORATED (US) 2000-02-29 US disclosed
US-5696251-A OLIGONUCLEOTIDES GEN-PROBE INCORPORATED (US) 1997-12-09 US disclosed
US-5656744-A COMPLEXING GEN-PROBE INCORPORATED (US) 1997-08-12 US disclosed
US-5585481-A VERSATILITY; NON-NUCLEOTIDE MONOMERIC UNIT HAVING A LIGAND AND FIRST AND SECOND COUPLING GROUPS WHICH ARE LINKED TO THE NON-NUCLEOTIDE MONOMERIC UNIT ; LABELS, INTERCALATORS, PROBES GEN-PROBE INCORPORATED (US) 1996-12-17 US disclosed
EP-0313219-B1 Non-nucleotide linking reagents for nucleotide probes GEN PROBE INC (US) 1996-05-08 EP disclosed
EP-0313219-A2 Non-nucleotide linking reagents for nucleotide probes GEN-PROBE INCORPORATED (US) 1989-04-26 EP disclosed
WO-1989002439-A1 NON-NUCLEOTIDE LINKING REAGENTS FOR NUCLEOTIDE PROBES ML TECHNOLOGY VENTURES, L.P. (US) 1989-03-23 WO disclosed