Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | QPCT | Q16769 | 3/20 | 0.40 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14557099 | 0.84 | KDM4E (0.43) | NPC1RAB9AKDM4EALDH1A1GAA | |
| SCHEMBL8044533 | 0.81 | IKBKB (0.36) | HDAC1HDAC2ALDH1A1QPCTSMN1; SMN2 | |
| SCHEMBL20214353 | 0.78 | KDM4E (0.69) | KIF11NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL20214059 | 0.78 | KDM4E (0.46) | KIF11HDAC1HDAC2NPC1RAB9A | |
| SCHEMBL8048162 | 0.77 | P2RY1 (0.41) | KIF11NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL969939 | 0.76 | KDM4E (0.59) | NPC1RAB9AKDM4EALDH1A1GAA | |
| SCHEMBL20214047 | 0.75 | HDAC1 (0.51) | KIF11HDAC1HDAC2NPC1RAB9A | |
| SCHEMBL8047389 | 0.75 | CA1 (0.49) | HDAC1HDAC2NPC1RAB9AKDM4E | |
| SCHEMBL28353374 | 0.75 | ALDH1A1 (0.48) | NPC1RAB9AKDM4EALDH1A1GAA | |
| SCHEMBL9360268 | 0.75 | GAA (0.60) | HDAC1HDAC2NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104292224-B | Containing replacing 1,3,4-thiophene () diazole thioether benzothiazole amide derivatives and its preparation method and application | 贵州大学 | 2016-07-06 | — | — | CN | disclosed |
| CN-104292224-A | Benzothiazole amide derivatives containing substituted 1,3,4-thiadiazole (oxadiazole) thioether as well as preparation method and application of derivatives | UNIV GUIZHOU | 2015-01-21 | — | — | CN | disclosed |
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |