Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 1/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 8/20 | 0.40 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.40 |
| ▸ | SCN1A | P35498 | 2/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31536884 | 0.80 | KDM4E (0.63) | SCN5ASCN2AKDM4EALDH1A1MAPT | |
| SCHEMBL14557099 | 0.80 | KDM4E (0.43) | KDM4EALDH1A1MAPTTP53HSD17B10 | |
| SCHEMBL8050331 | 0.77 | KIF11 (0.44) | P2RY1KDM4EALDH1A1MAPTNPC1 | |
| SCHEMBL13401040 | 0.77 | KDM4E (0.64) | KDM4EALDH1A1MAPTTP53HSD17B10 | |
| SCHEMBL23923175 | 0.76 | P2RY1 (0.39) | P2RY1ALPISCN5ANISCHSCN1A | |
| SCHEMBL25397725 | 0.76 | P2RY1 (0.39) | P2RY1ALPISCN5ANISCHSCN1A | |
| SCHEMBL8044729 | 0.74 | SMN1; SMN2 (0.43) | KDM4EMAPTCYP1A2NPC1RAB9A | |
| SCHEMBL22897980 | 0.73 | ALOX5AP (0.41) | P2RY1ALPISCN5ASCN1ASCN2A | |
| SCHEMBL29379022 | 0.71 | SCN5A (0.44) | P2RY1ALPISCN5ANISCHSCN1A | |
| SCHEMBL14424574 | 0.71 | RAB9A (0.68) | KDM4EALDH1A1MAPTTP53HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |