Di(Hydroxyethyl)Ether

Di(Hydroxyethyl)Ether

SCHEMBL8050398

C=C(C)C(=O)OOOC(=O)C(=C)C.OCCOCCO

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.42
TSHR P16473 6/20 0.42
MAPK1 P28482 1/20 0.42
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
ALDH1A1 P00352 3/20 0.39
HTT P42858 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10824635 0.89 THRB (0.42) THRBTSHRMAPK1MEN1KMT2A
Ethylene Glycol SCHEMBL2892017 0.87 ALDH1A1 (0.46) THRBTSHRALDH1A1
Di(Hydroxyethyl)Ether SCHEMBL464795 0.86 THRB (0.41) THRBTSHRMAPK1MEN1KMT2A
Di(Hydroxyethyl)Ether SCHEMBL984519 0.86 ALDH1A1 (0.43) THRBTSHRMAPK1MEN1KMT2A
Tetraethylene Glycol SCHEMBL1831944 0.84 THRB (0.44) THRBTSHRMAPK1MEN1KMT2A
Triethylene Glycol SCHEMBL135537 0.84 THRB (0.44) THRBTSHRMAPK1MEN1KMT2A
SCHEMBL10592245 0.84 THRB (0.44) THRBTSHRMAPK1MEN1KMT2A
SCHEMBL10595167 0.84 THRB (0.44) THRBTSHRMAPK1MEN1KMT2A
Di(Hydroxyethyl)Ether SCHEMBL27312004 0.83 TSHR (0.46) THRBTSHRMAPK1MEN1KMT2A
Di(Hydroxyethyl)Ether SCHEMBL1915248 0.82 THRB (0.47) THRBTSHRMAPK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6015845-A Binder for building structure ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 2000-01-18 US disclosed