Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 1.00 |
| ▸ | RAB9A | P51151 | 7/20 | 1.00 |
| ▸ | TP53 | P04637 | 5/20 | 1.00 |
| ▸ | NPC1 | O15118 | 6/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.81 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.81 |
| ▸ | GAA | P10253 | 1/20 | 0.79 |
| ▸ | POLB | P06746 | 1/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.68 |
| ▸ | TSHR | P16473 | 2/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.68 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.64 |
| ▸ | CA2 | P00918 | 1/20 | 0.64 |
| ▸ | CA9 | Q16790 | 1/20 | 0.64 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.62 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2813593 | 0.79 | S1PR1 (1.00) | SMN1; SMN2RAB9ATP53NPC1ALDH1A1 | |
| SCHEMBL27584128 | 0.78 | SMN1; SMN2 (0.80) | SMN1; SMN2RAB9ATP53NPC1ALDH1A1 | |
| SCHEMBL2772770 | 0.78 | S1PR1 (0.93) | SMN1; SMN2RAB9ATP53NPC1ALDH1A1 | |
| SCHEMBL18584968 | 0.78 | RAB9A (0.68) | SMN1; SMN2RAB9ATP53NPC1ALDH1A1 | |
| SCHEMBL23288078 | 0.78 | CASP3 (0.71) | SMN1; SMN2RAB9ATP53NPC1ALDH1A1 | |
| SCHEMBL30141977 | 0.77 | RAB9A (0.61) | SMN1; SMN2RAB9ATP53NPC1ALDH1A1 | |
| SCHEMBL4779549 | 0.77 | RAB9A (0.61) | SMN1; SMN2RAB9ATP53NPC1ALDH1A1 | |
| SCHEMBL5959963 | 0.77 | RAB9A (0.77) | SMN1; SMN2RAB9ATP53NPC1ALDH1A1 | |
| SCHEMBL7961699 | 0.77 | SMN1; SMN2 (0.81) | SMN1; SMN2RAB9ATP53NPC1ALDH1A1 | |
| SCHEMBL2771674 | 0.77 | S1PR1 (1.00) | SMN1; SMN2RAB9ATP53NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6130217-A | ANTITUMOR | PFIZER INC (US) | 2000-10-10 | — | — | US | disclosed |