SCHEMBL8050864

SCHEMBL8050864

CC(C)COc1cccc(C[O])c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRIM24 O15164 1/20 0.47
FAAH O00519 1/20 0.46
NR1H4 Q96RI1 1/20 0.45
SIRT2 Q8IXJ6 1/20 0.44
HIF1A Q16665 1/20 0.42
TAAR1 Q96RJ0 2/20 0.42
KAT6A Q92794 1/20 0.42
FOS P01100 1/20 0.41
JUN P05412 1/20 0.41
MAPT P10636 2/20 0.41
ALDH1A1 P00352 1/20 0.41
HTT P42858 1/20 0.41
GRM2 Q14416 1/20 0.41
MTNR1A P48039 3/20 0.41
MTNR1B P49286 3/20 0.41
MEN1 O00255 1/20 0.41
ALOX12 P18054 1/20 0.41
KMT2A Q03164 1/20 0.41
CHRM2 P08172 1/20 0.40
CHRM1 P11229 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8048492 0.86 NR1H4 (0.46) TRIM24FAAHNR1H4SIRT2TAAR1
SCHEMBL322457 0.84 KDM4E (0.50) TRIM24FAAHNR1H4TAAR1MAPT
SCHEMBL320945 0.84 TAAR1 (0.51) TRIM24FAAHNR1H4SIRT2HIF1A
SCHEMBL2967940 0.82 TRIM24 (0.55) TRIM24NR1H4SIRT2HIF1AKAT6A
SCHEMBL31538932 0.82 MAOB (0.49) TRIM24FAAHNR1H4SIRT2TAAR1
SCHEMBL6419825 0.82 FAAH (0.49) TRIM24FAAHNR1H4SIRT2HIF1A
SCHEMBL8050867 0.82 TSHR (0.49) TRIM24FAAHNR1H4SIRT2HIF1A
SCHEMBL272030 0.82 TRIM24 (0.43) TRIM24FAAHNR1H4SIRT2HIF1A
SCHEMBL20825574 0.82 MAOB (0.49) TRIM24FAAHNR1H4SIRT2TAAR1
SCHEMBL2702132 0.81 TRIM24 (0.44) TRIM24FAAHNR1H4SIRT2HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106232585-B Triaizine compounds and its medicinal usage 日本烟草产业株式会社 2019-04-02 CN disclosed
US-6106999-A SENSITIVITY TO GENERAL-PURPOSE VISIBLE LIGHT LASER, SO THAT HIGH-SPEED SCANNING EXPOSURE IS POSSIBLE BY LASER, AND EXTREMELY FINE HIGH RESOLUTION CAN BE OBTAINED; CAN BE USED FOR COATING OR PRINTING UNDER SAFELIGHT IRRADIATING CONDITIONS MITSUI CHEMICALS (JP) 2000-08-22 US disclosed