Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.35 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | CDC42 | P60953 | 1/20 | 0.34 |
| ▸ | RAC1 | P63000 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4698652 | 0.95 | SLC2A1 (0.41) | SLC2A1KDM4EHSD11B1MTNR1AMTNR1B | |
| SCHEMBL9939378 | 0.81 | SLC2A1 (0.42) | SLC2A1KDM4EHSD11B1MTNR1AMTNR1B | |
| SCHEMBL9938388 | 0.80 | SLC2A1 (0.41) | SLC2A1KDM4EHSD11B1MTNR1AMTNR1B | |
| SCHEMBL1360283 | 0.79 | SLC2A1 (0.43) | SLC2A1KDM4EHSD11B1MTNR1AMTNR1B | |
| SCHEMBL5981248 | 0.78 | CYP19A1 (0.38) | KDM4EHSP90AA1CYP1A2TSHR | |
| SCHEMBL8499219 | 0.77 | L3MBTL1 (0.50) | KDM4EHSD11B1PTGS1AKR1C3AKR1C2 | |
| SCHEMBL1180547 | 0.77 | MTNR1A (0.44) | SLC2A1MTNR1AMTNR1BCYP1A2 | |
| SCHEMBL15283286 | 0.77 | ABCC8 (0.43) | SLC2A1KDM4EHSD11B1RAD52CYP1A2 | |
| SCHEMBL13612566 | 0.77 | CYP1A2 (0.44) | SLC2A1KDM4EMTNR1AMTNR1BCYP1A2 | |
| SCHEMBL1304599 | 0.77 | MTNR1A (0.41) | KDM4EHSD11B1MTNR1AMTNR1BTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6147119-A | TREATING HYPOFOLLICULINIA DISORDERS; ANTICARCINOGENIC, ANTIMETASTASIS AND ANTITUMOR AGENTS; PREMENSTRUAL TENSION, MENOPAUSE, OSTEOPOROSIS | HOECHST MARION ROUSSEL (FR) | 2000-11-14 | — | — | US | disclosed |
| EP-0880496-A1 | BIPHENYL COMPOUNDS AND USE THEREOF AS OESTROGENIC AGENTS | HOECHST MARION ROUSSEL (FR) | 1998-12-02 | — | — | EP | disclosed |
| WO-1997028116-A1 | BIPHENYL COMPOUNDS AND USE THEREOF AS OESTROGENIC AGENTS | HOECHST MARION ROUSSEL (FR) | 1997-08-07 | — | — | WO | disclosed |