Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15088436 | 0.87 | MEN1 (0.54) | MEN1KMT2AHSD17B10ALDH1A1LMNA | |
| SCHEMBL373329 | 0.85 | LMNA (0.52) | MEN1KMT2AHSD17B10ALDH1A1LMNA | |
| SCHEMBL5568764 | 0.85 | LMNA (0.55) | MEN1KMT2AHSD17B10ALDH1A1LMNA | |
| SCHEMBL186987 | 0.85 | MEN1 (0.49) | MEN1KMT2AHSD17B10ALDH1A1LMNA | |
| SCHEMBL8043309 | 0.85 | ALDH1A1 (0.55) | MEN1KMT2AHSD17B10ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL7801197 | 0.84 | LMNA (0.51) | MEN1KMT2AHSD17B10ALDH1A1LMNA | |
| SCHEMBL7305720 | 0.81 | ALDH1A1 (0.48) | MEN1KMT2AHSD17B10ALDH1A1LMNA | |
| SCHEMBL3595473 | 0.79 | OPRM1 (0.47) | MEN1KMT2AHSD17B10ALDH1A1LMNA | |
| SCHEMBL4814054 | 0.78 | OPRM1 (0.46) | MEN1KMT2AHSD17B10ALDH1A1LMNA | |
| SCHEMBL6381424 | 0.77 | SLC6A4 (0.69) | OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009050248-A1 | SUBSTITUTED PIPERIDINO-DIHYDROTHIENOPYRIMIDINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-23 | — | — | WO | disclosed |