Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 4/20 | 0.70 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.65 |
| ▸ | CREB1 | P16220 | 2/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | ACHE | P22303 | 3/20 | 0.60 |
| ▸ | PPARG | P37231 | 1/20 | 0.60 |
| ▸ | BCHE | P06276 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.57 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.57 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.57 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.57 |
| ▸ | FLT3 | P36888 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30852834 | 0.96 | ABCB1 (0.65) | ABCB1ABCG2CREB1L3MBTL1MAPT | |
| SCHEMBL8062100 | 0.93 | MEN1 (0.71) | ABCB1ABCG2L3MBTL1MAPTACHE | |
| SCHEMBL21335353 | 0.91 | CREB1 (0.74) | ABCB1ABCG2CREB1L3MBTL1MAPT | |
| SCHEMBL8052863 | 0.91 | ABCB1 (0.64) | ABCB1ABCG2L3MBTL1ACHEBCHE | |
| SCHEMBL8052929 | 0.90 | ABCB1 (0.69) | ABCB1ABCG2L3MBTL1ACHEMEN1 | |
| SCHEMBL8068919 | 0.90 | ABCB1 (0.73) | ABCB1ABCG2L3MBTL1MAPTACHE | |
| SCHEMBL738489 | 0.89 | MEN1 (0.71) | ABCB1ABCG2L3MBTL1ACHEMEN1 | |
| SCHEMBL24514601 | 0.88 | ABCB1 (0.73) | ABCB1ABCG2L3MBTL1ACHEMEN1 | |
| SCHEMBL4649969 | 0.88 | ABCB1 (0.73) | ABCB1ABCG2L3MBTL1ACHEMEN1 | |
| SCHEMBL7156543 | 0.88 | ABCB1 (0.69) | ABCB1ABCG2L3MBTL1ACHEMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6806257-B1 | USING SUCH AS OROXYLIN A AND/OR WOGONIN; SEPTIC SHOCK, ANEURYSM, ANGIOTENSIN CONVERTING ENZYME INHIBITION; ANTIINFLAMMATORIES | BOARD OF TRUSTEES OF SOUTHERN ILLINOIS UNIVERSITY | 2004-10-19 | — | — | US | disclosed |
| WO-2001030342-A9 | FLAVONES AS INDUCIBLE NITRIC OXIDE SYNTHASE INHIBITORS, CYCLOOXYGENASE-2 INHIBITORS AND POTASSIUM CHANNEL ACTIVATORS | UNIV SOUTHERN ILLINOIS (US) | 2001-10-18 | — | — | WO | disclosed |
| WO-2001030342-A1 | FLAVONES AS INDUCIBLE NITRIC OXIDE SYNTHASE INHIBITORS, CYCLOOXYGENASE-2 INHIBITORS AND POTASSIUM CHANNEL ACTIVATORS | BOARD OF TRUSTEES OF SOUTHERN ILLINOIS UNIVERSITY (US) | 2001-05-03 | — | — | WO | disclosed |
| US-6025387-A | Gastroprotective flavone/flavanone compounds with therapeutic effect on inflammatory bowel disease | DONG A PHARMACEUTICAL CO., LTD. (KR) | 2000-02-15 | — | — | US | disclosed |
| EP-0915864-A1 | GASTROPROTECTIVE FLAVONE/FLAVANONE COMPOUNDS WITH THERAPEUTIC EFFECT ON INFLAMMATORY BOWEL DISEASE | Dong A Pharmaceutical Co. Ltd. (KR) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998004541-A1 | GASTROPROTECTIVE FLAVONE/FLAVANONE COMPOUNDS WITH THERAPEUTIC EFFECT ON INFLAMMATORY BOWEL DISEASE | DONG A PHARMACEUTICAL CO., LTD. (KR) | 1998-02-05 | — | — | WO | disclosed |