Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 5/20 | 0.33 |
| ▸ | NAAA | Q02083 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.30 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6514077 | 0.88 | KCNN4 (0.37) | KCNN4KIF11CNR1CNR2KDM4E | |
| SCHEMBL11290864 | 0.76 | KDM4E (0.33) | KIF11CNR2KDM4ELMNAGRIN1 | |
| SCHEMBL34050 | 0.74 | FOLH1 (0.43) | ALDH1A1HDAC2HDAC6 | |
| SCHEMBL34051 | 0.74 | FOLH1 (0.43) | ALDH1A1HDAC2HDAC6 | |
| SCHEMBL4579061 | 0.74 | KIF11 (0.44) | KIF11KDM4ETDP1LMNASMN1; SMN2 | |
| SCHEMBL7747362 | 0.74 | KIF11 (0.44) | KIF11KDM4ETDP1LMNASMN1; SMN2 | |
| SCHEMBL8734433 | 0.74 | KIF11 (0.44) | KIF11KDM4ETDP1LMNASMN1; SMN2 | |
| SCHEMBL5023008 | 0.73 | KIF11 (0.56) | KIF11ALDH1A1 | |
| SCHEMBL8170755 | 0.73 | KIF11 (0.47) | KCNN4KIF11 | |
| SCHEMBL5065127 | 0.70 | KIF11 (0.45) | KIF11LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6018019-A | IMMUNOGENIC SYNTHETIC PEPTIDES WHICH ARE USEFUL ALONE OR IN CONJUGATES IN VACCINES AGAINST HEMOPHILUS INFLUENZA INFECTION | CONNAUGHT LABORATORIES LIMITED (CA) | 2000-01-25 | — | — | US | disclosed |
| US-5972349-A | COUPLING SACCHARIDE TO SOLID POLYETHYLENE GLYCOL MONOMETHYL ETHER SUPPORT, REMOVING FIRST PROTECTING GROUP, COUPLING WITH THE REPEATING UNIT UNTIL THE DESIRED NUMBER OF REPEATING UNITS IN THE OLIGOMER HAS BEEN REACHED, TERMINATING | CONNAUGHT LABORATORIES LIMITED (CA) | 1999-10-26 | — | — | US | disclosed |
| US-5679352-A | Synthetic Haemophilus influenzae conjugate vaccine | CONNAUGHT LABORATORIES LIMITED (CA) | 1997-10-21 | — | — | US | disclosed |
| EP-0625203-A1 | SYNTHETIC HAEMOPHILUS INFLUENZAE CONJUGATE VACCINE | CONNAUGHT LABORATORIES LIMITED (CA) | 1994-11-23 | — | — | EP | disclosed |
| WO-1993015205-A2 | SYNTHETIC HAEMOPHILUS INFLUENZAE CONJUGATE VACCINE | CONNAUGHT LABORATORIES LIMITED (CA) | 1993-08-05 | — | — | WO | disclosed |