Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 6/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CTSL | P07711 | 2/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | CTSS | P25774 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 1/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | GRN | P28799 | 2/20 | 0.48 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4465251 | 0.86 | CTSL (0.67) | CA2CA1CTSLCTSBCTSS | |
| SCHEMBL2158900 | 0.86 | CTSL (0.67) | CA2CA1CTSLCTSBCTSS | |
| SCHEMBL2158906 | 0.86 | CTSL (0.67) | CA2CA1CTSLCTSBCTSS | |
| SCHEMBL27885368 | 0.84 | SLC1A2 (0.54) | ACEPTPN1CA2CA1CTSL | |
| SCHEMBL1640054 | 0.84 | NAALAD2 (0.58) | ACEPTPN1CA2CA1CTSL | |
| SCHEMBL27885367 | 0.84 | SLC1A2 (0.54) | ACEPTPN1CA2CA1CTSL | |
| SCHEMBL2791574 | 0.83 | CA2 (0.66) | ACEPTPN1CA2CA1SLC1A2 | |
| SCHEMBL2792747 | 0.83 | CA2 (0.66) | ACEPTPN1CA2CA1SLC1A2 | |
| SCHEMBL9943491 | 0.83 | CA2 (0.66) | ACEPTPN1CA2CA1SLC1A2 | |
| SCHEMBL11063949 | 0.81 | ACE (0.52) | ACEPTPN1CA2CA1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0804413-B1 | NITROGEN MUSTARD PRODRUGS WITH NOVEL LIPOPHILIC PROTECTING GROUPS, AND PROCESSES FOR THEIR PRODUCTION | CANCER RES CAMPAIGN TECH (GB) | 2000-05-17 | — | — | EP | disclosed |