SCHEMBL27885367

SCHEMBL27885367

NC(C[C@H](NC(=O)c1ccccc1)C(=O)O)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SLC1A2 P43004 2/20 0.54
CA2 P00918 7/20 0.50
CA1 P00915 4/20 0.50
ACE P12821 2/20 0.49
PTPN1 P18031 1/20 0.48
CTSL P07711 2/20 0.47
CTSB P07858 1/20 0.47
CTSS P25774 1/20 0.47
CTSK P43235 1/20 0.47
SLC1A3 P43003 1/20 0.46
SLC1A1 P43005 1/20 0.46
GRM2 Q14416 1/20 0.46
GRM3 Q14832 1/20 0.46
ITGB3 P05106 1/20 0.46
ITGA2B P08514 1/20 0.46
IDO1 P14902 1/20 0.46
LTA4H P09960 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27885368 1.00 SLC1A2 (0.54) SLC1A2CA2CA1ACEPTPN1
SCHEMBL8053213 0.84 ACE (0.52) SLC1A2CA2CA1ACEPTPN1
SCHEMBL8787239 0.81 SLC1A2 (0.49) SLC1A2CA2CA1ACEPTPN1
D-Phenylalanine SCHEMBL10761946 0.81 CA2 (0.65) CA2CA1ACEPTPN1CTSL
Phenylalanine SCHEMBL10760080 0.81 CA2 (0.65) CA2CA1ACEPTPN1CTSL
SCHEMBL4465251 0.81 CTSL (0.67) CA2CA1CTSLCTSBCTSS
SCHEMBL2158906 0.81 CTSL (0.67) CA2CA1CTSLCTSBCTSS
SCHEMBL2158900 0.81 CTSL (0.67) CA2CA1CTSLCTSBCTSS
SCHEMBL30743610 0.81 SLC1A2 (0.54) SLC1A2CA2CA1ACEPTPN1
SCHEMBL1640054 0.80 NAALAD2 (0.58) CA2CA1ACEPTPN1CTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12564592-B1 Injectable leucovorin formulations and methods of preparing same Riconpharma LLC 2026-03-03 US claimed
CN-102612358-A Stabilised particles comprising 5-methyl-(6s)-tetrahydrofolate BAYER SCHERING PHARMA AG 2012-07-25 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12564592-B1 Injectable leucovorin formulations and methods of preparing same FGF23, MTHFD1, SI SLC1A2 2031/4885CA2 286/4885CA1 971/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.