Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 12/20 | 0.39 |
| ▸ | KDM6B | O15054 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4D | Q6B0I6 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4A | O75164 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CCNC | P24863 | 2/20 | 0.37 |
| ▸ | CDK8 | P49336 | 2/20 | 0.37 |
| ▸ | AXL | P30530 | 1/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL526501 | 0.81 | CCNC (0.36) | KDM4CKDM6BKDM4EALDH1A1KDM4D | |
| SCHEMBL29920601 | 0.78 | KDM4C (0.59) | KDM4CKDM6BKDM4EALDH1A1KDM4D | |
| SCHEMBL480991 | 0.78 | KDM4C (0.59) | KDM4CKDM6BKDM4EALDH1A1KDM4D | |
| Hydrochloric Acid SCHEMBL2892062 | 0.77 | KDM4C (0.57) | KDM4CKDM6BKDM4EALDH1A1KDM4D | |
| SCHEMBL25207609 | 0.77 | CCNC (0.43) | KDM4CKDM6BKDM4EALDH1A1KDM4D | |
| SCHEMBL19381848 | 0.74 | TDP1 (0.42) | KDM4CKDM6BKDM4EALDH1A1KDM4D | |
| SCHEMBL17425264 | 0.74 | LOXL2 (0.41) | KDM4CKDM6BKDM4EALDH1A1KDM4D | |
| SCHEMBL11341427 | 0.72 | CYP2A6 (0.47) | KDM4CKDM6BKDM4EALDH1A1KDM4D | |
| SCHEMBL5700120 | 0.72 | TDP1 (0.55) | KDM4CKDM6BKDM4EALDH1A1KDM4D | |
| SCHEMBL16897000 | 0.72 | CCNC (0.43) | KDM4CKDM6BKDM4EALDH1A1KDM4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120071514-A1 | BENZOXAZOLONE DERIVATIVES AS ALDOSTERONE SYNTHASE INHIBITORS | NOVARTIS AG (CH) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071514-A1 | BENZOXAZOLONE DERIVATIVES AS ALDOSTERONE SYNTHASE INHIBITORS | CYP11B2, CYP11B1, CYP21A2 | KDM4C 3010/4885KDM6B 2827/4885KDM4E 2762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.