SCHEMBL8053871

SCHEMBL8053871

C=C(C)C(=O)OCCOCCNc1ccc2ccccc2c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.44
CYP1A2 P05177 3/20 0.44
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
CYP2C19 P33261 2/20 0.44
HIF1A Q16665 2/20 0.44
KDM4E B2RXH2 2/20 0.44
THRB P10828 1/20 0.43
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
HSD17B10 Q99714 1/20 0.42
HDAC3 O15379 1/20 0.40
HDAC4 P56524 1/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC7 Q8WUI4 1/20 0.40
HDAC2 Q92769 1/20 0.40
HDAC10 Q969S8 1/20 0.40
HDAC11 Q96DB2 1/20 0.40
HDAC8 Q9BY41 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8068096 0.96 THRB (0.42) ALDH1A1CYP1A2MEN1KMT2ACYP2C19
SCHEMBL116991 0.81 KDM4E (0.62) ALDH1A1MEN1KMT2AKDM4ETHRB
SCHEMBL25123493 0.81 KDM4E (0.62) ALDH1A1MEN1KMT2AKDM4ETHRB
SCHEMBL19360462 0.80 HRH3 (0.52) ALDH1A1MEN1KMT2AKDM4ETHRB
SCHEMBL19360464 0.80 HRH3 (0.52) ALDH1A1MEN1KMT2AKDM4ETHRB
SCHEMBL8068053 0.79 CYP1A2 (0.51) ALDH1A1CYP1A2MEN1KMT2AKDM4E
SCHEMBL18926601 0.77 HRH3 (0.47) CYP1A2MEN1KMT2ACYP2C19KDM4E
SCHEMBL305728 0.77 POLB (0.44) ALDH1A1KDM4ETHRBHSD17B10MAPT
SCHEMBL8063231 0.77 ALDH1A1 (0.53) ALDH1A1CYP1A2MEN1KMT2ACYP2C19
SCHEMBL2033345 0.76 KDM4E (0.54) ALDH1A1MEN1KMT2AKDM4EHDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5948268-A DISSOLVING IN WATER TO BE TREATED A POLYMER FORMED FROM WATER SOLUBLE MONOMER UNITS COMPRISING A (POLY)ALKYLENE OXIDE END CAPPED WITH AN ADDITION POLYMERIZABLE GROUP AT ONE END AND AN INTENSELY FLUORESCENT GROUP AT OTHER NIPPON SHOKUBAI CO., LTD. (JP) 1999-09-07 US claimed
EP-0761604-B1 An agent for water treatment NIPPON CATALYTIC CHEM IND (JP) 2000-06-14 EP disclosed
EP-0761604-A2 An agent for water treatment NIPPON SHOKUBAI CO., LTD. (JP) 1997-03-12 EP disclosed