Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 15/20 | 0.53 |
| ▸ | DRD3 | P35462 | 3/20 | 0.53 |
| ▸ | DRD2 | P14416 | 2/20 | 0.53 |
| ▸ | AGER | Q15109 | 1/20 | 0.43 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8051372 | 0.92 | DRD4 (0.54) | DRD4DRD3DRD2 | |
| SCHEMBL8039975 | 0.92 | DRD4 (0.50) | DRD4DRD3DRD2AGERABCC8 | |
| SCHEMBL8040073 | 0.91 | DRD4 (0.53) | DRD4DRD3DRD2 | |
| SCHEMBL8058060 | 0.86 | HTR4 (0.58) | DRD4DRD3DRD2 | |
| SCHEMBL8040144 | 0.78 | HTR4 (0.57) | — | |
| SCHEMBL8054707 | 0.78 | HTR4 (0.53) | DRD2 | |
| SCHEMBL8055027 | 0.77 | HTR4 (0.64) | — | |
| SCHEMBL8040220 | 0.77 | HTR4 (0.58) | — | |
| SCHEMBL8040211 | 0.77 | CNR2 (0.47) | DRD2 | |
| SCHEMBL11549582 | 0.75 | DRD4 (0.75) | DRD4DRD3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0998469-A1 | BENZAMIDE CYCLOALKYL STIMULATING HIGH AND LOW GASTROINTESTINAL MOTRICITY | Laboratoires Jacques Logeais (FR) | 2000-05-10 | — | — | EP | disclosed |
| WO-1999005133-A1 | BENZAMIDE CYCLOALKYL STIMULATING HIGH AND LOW GASTROINTESTINAL MOTRICITY | LABORATOIRES JACQUES LOGEAIS (FR) | 1999-02-04 | — | — | WO | disclosed |