Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 7/20 | 0.58 |
| ▸ | HTR3A | P46098 | 2/20 | 0.56 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.56 |
| ▸ | HTR3B | O95264 | 1/20 | 0.56 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.56 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8040144 | 0.92 | HTR4 (0.57) | HTR4HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL8055027 | 0.91 | HTR4 (0.64) | HTR4HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL8054707 | 0.91 | HTR4 (0.53) | HTR4HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL8040211 | 0.90 | CNR2 (0.47) | HTR4HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL8040220 | 0.90 | HTR4 (0.58) | HTR4HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL8054528 | 0.86 | DRD4 (0.53) | DRD2DRD4DRD3 | |
| SCHEMBL8050559 | 0.82 | CNR2 (0.50) | HTR4HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL8051399 | 0.81 | CNR2 (0.48) | HTR4HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL8051372 | 0.78 | DRD4 (0.54) | DRD2DRD4DRD3 | |
| SCHEMBL8039975 | 0.77 | DRD4 (0.50) | HTR4HTR3AHTR3EHTR3BHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0998469-A1 | BENZAMIDE CYCLOALKYL STIMULATING HIGH AND LOW GASTROINTESTINAL MOTRICITY | Laboratoires Jacques Logeais (FR) | 2000-05-10 | — | — | EP | disclosed |
| WO-1999005133-A1 | BENZAMIDE CYCLOALKYL STIMULATING HIGH AND LOW GASTROINTESTINAL MOTRICITY | LABORATOIRES JACQUES LOGEAIS (FR) | 1999-02-04 | — | — | WO | disclosed |