Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.35 |
| ▸ | CTSA | P10619 | 1/20 | 0.35 |
| ▸ | GCGR | P47871 | 3/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.33 |
| ▸ | CCNC | P24863 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
| ▸ | CHUK | O15111 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8054627 | 0.82 | — | — | |
| SCHEMBL22802379 | 0.63 | NLRP3 (0.53) | AKR1C3AKR1C2MAPK14CTSAPTGDR2 | |
| SCHEMBL28133835 | 0.60 | ALDH1A1 (0.56) | AKR1C3AKR1C2MAPK14GCGRIKBKB | |
| SCHEMBL21052450 | 0.60 | HTT (0.49) | MAPK14GCGRIKBKBCHUKALDH1A1 | |
| SCHEMBL3741185 | 0.60 | PTGDR2 (0.49) | AKR1C3AKR1C2MAPK14GCGRPTGDR2 | |
| SCHEMBL1453561 | 0.60 | LMNA (0.31) | — | |
| SCHEMBL1452325 | 0.59 | — | — | |
| Hydrochloric Acid SCHEMBL14840881 | 0.59 | ALDH1A1 (0.55) | AKR1C3AKR1C2MAPK14GCGRIKBKB | |
| SCHEMBL2645320 | 0.59 | MAPK14 (0.54) | AKR1C3AKR1C2MAPK14GCGRIKBKB | |
| SCHEMBL30664877 | 0.59 | MAPK14 (0.59) | MAPK14GCGRALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6020379-A | Position 7 substituted indenyl-3-acetic acid derivatives and amides thereof for the treatment of neoplasia | CELL PATHWAYS, INC. (US) | 2000-02-01 | — | — | US | disclosed |