Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.46 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20954435 | 0.85 | MTNR1A (0.47) | MTNR1AMTNR1BPAOXMAPK1KDM4E | |
| SCHEMBL9853199 | 0.85 | MTNR1A (0.50) | MTNR1AMTNR1BPAOXMAPK1KDM4E | |
| SCHEMBL11923029 | 0.81 | MTNR1A (0.47) | MTNR1AMTNR1BPAOXMAPK1KDM4E | |
| SCHEMBL26009556 | 0.81 | MTNR1A (0.47) | MTNR1AMTNR1BPAOXMAPK1KDM4E | |
| SCHEMBL6037070 | 0.81 | CA2 (0.39) | MTNR1AMTNR1BKDM4ETSHRSMN1; SMN2 | |
| SCHEMBL27853186 | 0.79 | MTNR1A (0.50) | MTNR1AMTNR1BPAOXMAPK1KDM4E | |
| SCHEMBL20123390 | 0.79 | PAOX (0.45) | MTNR1AMTNR1BPAOXMAPK1KDM4E | |
| SCHEMBL28337342 | 0.78 | MAPK1 (0.46) | MTNR1AMTNR1BPAOXMAPK1KDM4E | |
| SCHEMBL18295824 | 0.78 | — | — | |
| SCHEMBL279485 | 0.78 | MAPK1 (0.50) | MTNR1AMTNR1BPAOXMAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015011-A1 | PEPTIDE NUCLEIC ACIDS HAVING ANTIBACTERIAL ACTIVITY | NIELSEN, Peter Eigil (DK) | 2000-07-05 | — | — | EP | claimed |
| WO-1999013893-A1 | PEPTIDE NUCLEIC ACIDS HAVING ANTIBACTERIAL ACTIVITY | ISIS PHARMACEUTICALS, INC. (US) | 1999-03-25 | — | — | WO | claimed |
| EP-0699208-A1 | NOVEL PEPTIDE NUCLEIC ACIDS | NIELSEN, Peter Eigil (DK) | 1996-03-06 | — | — | EP | disclosed |
| WO-1994025477-A2 | NOVEL PEPTIDE NUCLEIC ACIDS | NIELSEN PETER E (DK) | 1994-11-10 | — | — | WO | disclosed |