Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 2/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.39 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8965229 | 0.86 | PABPC1 (0.37) | PABPC1APOBEC3AAPOBEC3GEIF4HCYP2D6 | |
| SCHEMBL8965989 | 0.86 | PABPC1 (0.37) | PABPC1APOBEC3AAPOBEC3GEIF4HCYP2D6 | |
| SCHEMBL8965696 | 0.85 | NPC1 (0.37) | PABPC1APOBEC3AAPOBEC3GEIF4HCYP2D6 | |
| SCHEMBL8965936 | 0.84 | TRPA1 (0.38) | PABPC1APOBEC3AAPOBEC3GEIF4HCYP2D6 | |
| SCHEMBL8965968 | 0.83 | CYP2D6 (0.36) | PABPC1APOBEC3AAPOBEC3GEIF4HCYP2D6 | |
| SCHEMBL8965910 | 0.83 | CYP2D6 (0.36) | PABPC1APOBEC3AAPOBEC3GEIF4HCYP2D6 | |
| SCHEMBL8965364 | 0.83 | CYP2D6 (0.38) | PABPC1APOBEC3AAPOBEC3GEIF4HCYP2D6 | |
| SCHEMBL8965177 | 0.83 | CYP2D6 (0.38) | PABPC1APOBEC3AAPOBEC3GEIF4HCYP2D6 | |
| SCHEMBL8056836 | 0.82 | HTT (0.42) | PABPC1APOBEC3AAPOBEC3GEIF4HCYP2D6 | |
| SCHEMBL8965651 | 0.82 | HTT (0.42) | PABPC1APOBEC3AAPOBEC3GEIF4HCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758643-B1 | Process for the preparation of ortho-nitro-benzonitriles | CLARIANT GMBH (DE) | 2000-05-17 | — | — | EP | disclosed |
| US-5705674-A | Process for preparing ortho-nitrobenzonitriles | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-01-06 | — | — | US | disclosed |
| EP-0758643-A2 | Process for the preparation of ortho-nitro-benzonitriles | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-02-19 | — | — | EP | disclosed |
| US-5510528-A | Preparation of halomethylbenzoly cyanides and novel halomethylbenzoyl cyanides | BASF AKTIENGESELLSCHAFT (DE) | 1996-04-23 | — | — | US | disclosed |
| US-5446199-A | Preparation of halomethylbenzoyl cyanides and novel halomethylbenzoyl cyanides | BASF AKTIENGESELLSCHAFT (DE) | 1995-08-29 | — | — | US | disclosed |