SCHEMBL8965989

SCHEMBL8965989

CC(C)C(C)C[N+]1(Cc2ccccc2)CCCCCC1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PABPC1 P11940 2/20 0.37
APOBEC3A P31941 2/20 0.37
APOBEC3G Q9HC16 2/20 0.37
EIF4H Q15056 1/20 0.37
TRPA1 O75762 2/20 0.37
CYP2D6 P10635 2/20 0.35
SLC22A2 O15244 1/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33
LMNA P02545 1/20 0.33
HTT P42858 1/20 0.33
CHRNA7 P36544 2/20 0.33
CHRNB2 P17787 1/20 0.33
CHRNA4 P43681 1/20 0.33
HIF1A Q16665 1/20 0.33
SLC6A2 P23975 2/20 0.32
TAAR1 Q96RJ0 2/20 0.32
MAOA P21397 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8965229 1.00 PABPC1 (0.37) PABPC1APOBEC3AAPOBEC3GEIF4HTRPA1
SCHEMBL8965936 0.98 TRPA1 (0.38) PABPC1APOBEC3AAPOBEC3GEIF4HTRPA1
SCHEMBL8054698 0.86 PABPC1 (0.39) PABPC1APOBEC3AAPOBEC3GEIF4HCYP2D6
SCHEMBL8965383 0.85 TRPA1 (0.36) APOBEC3AAPOBEC3GTRPA1CYP2D6CHRNB4
SCHEMBL8965696 0.82 NPC1 (0.37) PABPC1APOBEC3AAPOBEC3GEIF4HTRPA1
SCHEMBL8965968 0.81 CYP2D6 (0.36) PABPC1APOBEC3AAPOBEC3GEIF4HCYP2D6
SCHEMBL8965910 0.81 CYP2D6 (0.36) PABPC1APOBEC3AAPOBEC3GEIF4HCYP2D6
SCHEMBL8056836 0.80 HTT (0.42) PABPC1APOBEC3AAPOBEC3GEIF4HCYP2D6
SCHEMBL8965651 0.80 HTT (0.42) PABPC1APOBEC3AAPOBEC3GEIF4HCYP2D6
SCHEMBL8965111 0.80 NPC1 (0.38) PABPC1APOBEC3AAPOBEC3GEIF4HCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0619300-B1 Process for the preparation of halogenmethylbenzoyl cyanides and halogenmethyl benzoylcyanides BASF AG (DE) 1996-12-27 EP disclosed
US-5510528-A Preparation of halomethylbenzoly cyanides and novel halomethylbenzoyl cyanides BASF AKTIENGESELLSCHAFT (DE) 1996-04-23 US disclosed
US-5446199-A Preparation of halomethylbenzoyl cyanides and novel halomethylbenzoyl cyanides BASF AKTIENGESELLSCHAFT (DE) 1995-08-29 US disclosed
EP-0619300-A2 Process for the preparation of halogenmethylbenzoyl cyanides and halogenmethyl benzoylcyanides BASF Aktiengesellschaft (DE) 1994-10-12 EP disclosed