Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8054773 | 0.65 | — | — | |
| SCHEMBL8086690 | 0.63 | — | — | |
| SCHEMBL8087978 | 0.63 | — | — | |
| SCHEMBL468475 | 0.60 | — | — | |
| SCHEMBL9321998 | 0.60 | — | — | |
| SCHEMBL7694255 | 0.59 | — | — | |
| SCHEMBL7690191 | 0.59 | — | — | |
| SCHEMBL5859274 | 0.59 | ACHE (0.45) | — | |
| Hydrochloric Acid SCHEMBL8055085 | 0.58 | — | — | |
| SCHEMBL8079712 | 0.58 | NOS3 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000073-A1 | METHOD FOR PRODUCING METALLOCENES | Basell Polyolefine GmbH (DE) | 2000-05-17 | — | — | EP | disclosed |
| WO-1999005152-A1 | METHOD FOR PRODUCING METALLOCENES | TARGOR GMBH (DE) | 1999-02-04 | — | — | WO | disclosed |