Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | POLM | Q9NP87 | 1/20 | 0.40 |
| ▸ | POLK | Q9UBT6 | 1/20 | 0.40 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.40 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.40 |
| ▸ | TOP2A | P11388 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8057870 | 0.99 | ALOX15 (0.44) | ALOX15EPHX1PPARGPPARAKDM4E | |
| SCHEMBL9735599 | 0.91 | ALOX15 (0.51) | ALOX15EPHX1PPARGPPARAKDM4E | |
| SCHEMBL8040318 | 0.91 | MAOA (0.42) | ALOX15EPHX1MAOAHDAC1BACE1 | |
| SCHEMBL9737235 | 0.90 | ALOX15 (0.50) | ALOX15EPHX1PPARGPPARAKDM4E | |
| SCHEMBL9735531 | 0.83 | POLM (0.50) | ALOX15PPARGPPARAKDM4EPOLM | |
| SCHEMBL9735533 | 0.83 | POLM (0.50) | ALOX15PPARGPPARAKDM4EPOLM | |
| SCHEMBL9734923 | 0.81 | ALOX15 (0.48) | ALOX15EPHX1KDM4EMAOAHDAC1 | |
| SCHEMBL27527333 | 0.80 | SMPD1 (0.46) | EPHX1MEN1KMT2AHDAC1 | |
| SCHEMBL8040562 | 0.80 | SMPD1 (0.46) | EPHX1MEN1KMT2AHDAC1 | |
| SCHEMBL27815409 | 0.79 | MAOA (0.60) | EPHX1KMT2AMAOAHDAC1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0428442-B1 | Composition comprising derivatives of 6- or 7-hydroxyindole as couplers and dyeing processes using same | OREAL (FR) | 1994-08-31 | — | — | EP | claimed |
| EP-0428442-A1 | Composition comprising derivatives of 6- or 7-hydroxyindole as couplers and dyeing processes using same | L'OREAL (FR) | 1991-05-22 | — | — | EP | claimed |
| US-6090160-A | USE OF THE 6- OR 7-HYDROXYINDOLE COUPLER ENABLES DYEINGS WITH RESISTANCE TO LIGHT, TO WASHING, TO THE WEATHER AND TO PERSPIRATION TO BE OBTAINED, IN PARTICULAR WHEN USED WITH P-PHENYLENEDIAMINE DERIVATIVES | L'OREAL (FR) | 2000-07-18 | — | — | US | disclosed |
| EP-0428442-B1 | Composition comprising derivatives of 6- or 7-hydroxyindole as couplers and dyeing processes using same | OREAL (FR) | 1994-08-31 | — | — | EP | disclosed |
| EP-0428442-A1 | Composition comprising derivatives of 6- or 7-hydroxyindole as couplers and dyeing processes using same | L'OREAL (FR) | 1991-05-22 | — | — | EP | disclosed |