Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CRHR1 | P34998 | 4/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6723521 | 0.81 | KCNH3 (0.54) | KCNH3ALDH1A1LMNANPSR1MAPT | |
| SCHEMBL9913720 | 0.81 | ALDH1A1 (0.68) | KCNH3MAPK1TP53TSHRHTT | |
| SCHEMBL7535691 | 0.77 | TP53 (0.46) | KCNH3MAPK1TP53TSHRHTT | |
| SCHEMBL6641031 | 0.76 | SLC29A1 (0.51) | KCNH3SMN1; SMN2CRHR1KMT2ACA1 | |
| SCHEMBL13784030 | 0.76 | ALDH1A1 (0.62) | KCNH3MAPK1TP53TSHRHTT | |
| SCHEMBL11668680 | 0.74 | GAA (0.50) | MAPK1TP53TSHRALDH1A1LMNA | |
| SCHEMBL6716597 | 0.74 | SLC29A1 (0.50) | KCNH3SMN1; SMN2CRHR1KMT2ACA1 | |
| SCHEMBL12732294 | 0.73 | KCNH3 (0.90) | KCNH3CA1CA2CA9 | |
| SCHEMBL9913724 | 0.73 | SLC29A1 (0.45) | KCNH3MAPK1TP53TSHRHTT | |
| SCHEMBL9913739 | 0.73 | KCNH3 (0.90) | KCNH3CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6130332-A | USING A GROUP 8 METAL CATALYST AND ALDEHYDES OR KETONE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2000-10-10 | — | — | US | disclosed |
| EP-0760369-A1 | PROCESS FOR ALKYLATING TRIAZINE DERIVATIVE | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1997-03-05 | — | — | EP | disclosed |