Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 7/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | CRHR1 | P34998 | 4/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6723521 | 0.82 | KCNH3 (0.54) | GAAMAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL14118021 | 0.78 | KCNH3 (0.46) | GAAMAPTMEN1KMT2AKDM4E | |
| SCHEMBL7754258 | 0.76 | NPSR1 (0.57) | GAASMN1; SMN2NPSR1 | |
| SCHEMBL11292840 | 0.76 | MAPT (0.50) | MAPTALDH1A1SMN1; SMN2TSHRAOC3 | |
| SCHEMBL16010978 | 0.75 | MAPT (0.49) | GAAMAPTMEN1KMT2AKDM4E | |
| SCHEMBL8054907 | 0.74 | KCNH3 (0.52) | MAPTKMT2ACRHR1ALDH1A1LMNA | |
| SCHEMBL8633855 | 0.72 | TSHR (0.42) | KDM4ECRHR1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL3393676 | 0.72 | TSHR (0.42) | GAAMAPTKMT2AKDM4ECRHR1 | |
| SCHEMBL11817842 | 0.68 | GBA1 (0.54) | GAAMAPTMEN1KMT2AKDM4E | |
| SCHEMBL11402745 | 0.68 | ALDH1A1 (0.51) | MAPTMEN1KMT2ACRHR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-52111584-A | — | — | None | — | — | JP | disclosed |
| JP-S52111584-A | NOVEL HYDRAZINO-S-TRIAZINE DERIVATIVES AND METHOD OF PREPARING THE SAM E | TEIJIN LTD | 1977-09-19 | — | — | JP | disclosed |