Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.31 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8054972 | 0.89 | SMPD1 (0.40) | CYP3A4ALDH1A1TSHRHPGDATM | |
| SCHEMBL5685934 | 0.70 | CYP3A4 (0.50) | CYP3A4ALDH1A1TSHRHPGDSMN1; SMN2 | |
| SCHEMBL3913186 | 0.69 | ALDH1A1 (0.39) | ALDH1A1TSHRHPGDATMSMN1; SMN2 | |
| SCHEMBL127570 | 0.69 | CYP3A4 (0.48) | CYP3A4TSHRHPGDSMN1; SMN2SMPD1 | |
| SCHEMBL24924894 | 0.66 | ALDH1A1 (0.43) | ALDH1A1TSHRHPGDATMHCAR2 | |
| SCHEMBL15925689 | 0.66 | ALDH1A1 (0.43) | CYP3A4ALDH1A1TSHRHPGDATM | |
| SCHEMBL37202 | 0.65 | CYP3A4 (0.47) | CYP3A4TSHRHPGDSMN1; SMN2SMPD1 | |
| SCHEMBL3902661 | 0.65 | TSHR (0.43) | CYP3A4ALDH1A1TSHRHPGDHCAR2 | |
| SCHEMBL4447305 | 0.63 | SMPD1 (0.48) | CYP3A4TSHRSMPD1LPAR3LPAR1 | |
| SCHEMBL28520717 | 0.63 | CYP3A4 (0.38) | CYP3A4TSHRSMPD1LPAR3LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6030543-A | A TRIALKOXYALKYL PHOSPHATE ESTER, A TRIALKYL PHOSPHATE OR A MIXTURE THEREOF, AND A TRIALKYL PHOSPHITE ESTER HAVING A POUR POINT OF LESS THAN-50.DEGREE. C.; EXTREME TEMPERATURE LUBRICANTS; WEAR, CORROSION AND HEAT RESISTANCES; RHEOLOGY | GREAT LAKES CHEMICAL CORPORATION (US) | 2000-02-29 | — | — | US | claimed |
| US-20160201001-A1 | ADDITIVE FOR OIL-BASED LUBRICANTS HAVING IMPROVED EXTREME PRESSURE PROPERTIES | Terralub GmbH (DE) | 2016-07-14 | — | — | US | disclosed |