Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 6/20 | 0.40 |
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.37 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8054971 | 0.89 | CYP3A4 (0.38) | SMPD1LPAR3LPAR1LPAR2ALDH1A1 | |
| SCHEMBL4447305 | 0.73 | SMPD1 (0.48) | SMPD1LPAR3LPAR1LPAR2TSHR | |
| SCHEMBL29236716 | 0.72 | LPAR3 (0.50) | SMPD1LPAR3LPAR1LPAR2 | |
| SCHEMBL127571 | 0.72 | SMPD1 (0.47) | SMPD1LPAR3LPAR1LPAR2TSHR | |
| SCHEMBL3913186 | 0.68 | ALDH1A1 (0.39) | ALDH1A1TSHRHPGDATMHCAR2 | |
| SCHEMBL37204 | 0.67 | SMPD1 (0.42) | SMPD1LPAR3LPAR1LPAR2TSHR | |
| SCHEMBL11525690 | 0.66 | LPAR3 (0.55) | SMPD1LPAR3LPAR1LPAR2 | |
| SCHEMBL28520717 | 0.66 | CYP3A4 (0.38) | SMPD1LPAR3LPAR1LPAR2TSHR | |
| Phosphoric Acid SCHEMBL27986970 | 0.66 | SMPD1 (0.41) | SMPD1LPAR3LPAR1LPAR2TSHR | |
| SCHEMBL24924894 | 0.65 | ALDH1A1 (0.43) | ALDH1A1TSHRHPGDATMHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6030543-A | A TRIALKOXYALKYL PHOSPHATE ESTER, A TRIALKYL PHOSPHATE OR A MIXTURE THEREOF, AND A TRIALKYL PHOSPHITE ESTER HAVING A POUR POINT OF LESS THAN-50.DEGREE. C.; EXTREME TEMPERATURE LUBRICANTS; WEAR, CORROSION AND HEAT RESISTANCES; RHEOLOGY | GREAT LAKES CHEMICAL CORPORATION (US) | 2000-02-29 | — | — | US | claimed |
| US-20160201001-A1 | ADDITIVE FOR OIL-BASED LUBRICANTS HAVING IMPROVED EXTREME PRESSURE PROPERTIES | Terralub GmbH (DE) | 2016-07-14 | — | — | US | disclosed |