Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13253652 | 0.71 | MAOB (0.39) | MAOBMAOATAAR1 | |
| SCHEMBL3052073 | 0.68 | KDM1A (0.47) | MAOBMAOA | |
| SCHEMBL10751965 | 0.68 | SLC6A4 (0.44) | — | |
| SCHEMBL29374849 | 0.67 | MAOA (0.68) | DPP4MAOBMAOATAAR1 | |
| SCHEMBL11471276 | 0.65 | OPRM1 (0.40) | MAOBMAOA | |
| SCHEMBL11451164 | 0.65 | OPRM1 (0.40) | MAOBMAOA | |
| SCHEMBL12831141 | 0.65 | LMNA (0.52) | — | |
| SCHEMBL11451165 | 0.65 | OPRM1 (0.40) | MAOBMAOA | |
| SCHEMBL10208913 | 0.64 | DPP4 (0.70) | DPP4MAOBMAOATAAR1 | |
| Bromide SCHEMBL11471424 | 0.64 | LMNA (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009050248-A1 | SUBSTITUTED PIPERIDINO-DIHYDROTHIENOPYRIMIDINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-23 | — | — | WO | disclosed |