Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.44 |
| ▸ | MMP2 | P08253 | 8/20 | 0.42 |
| ▸ | MMP1 | P03956 | 3/20 | 0.42 |
| ▸ | MMP3 | P08254 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6159691 | 0.89 | CTSK (0.45) | CTSK | |
| SCHEMBL8054967 | 0.88 | MMP2 (0.42) | MMP2MMP1MMP3 | |
| SCHEMBL8057878 | 0.88 | MMP2 (0.54) | MMP2MMP1MMP3 | |
| SCHEMBL8053746 | 0.88 | MMP2 (0.54) | MMP2MMP1MMP3 | |
| SCHEMBL8053893 | 0.88 | MMP2 (0.54) | MMP2MMP1MMP3 | |
| SCHEMBL8060170 | 0.88 | MMP2 (0.54) | MMP2MMP1MMP3 | |
| SCHEMBL8777260 | 0.79 | MMP2 (0.55) | MMP2MMP1MMP3 | |
| SCHEMBL7075178 | 0.76 | MMP2 (0.41) | MMP2MMP1MMP3 | |
| SCHEMBL7075177 | 0.76 | MMP2 (0.41) | MMP2MMP1MMP3 | |
| SCHEMBL8086308 | 0.76 | MMP2 (0.39) | CTSKMMP2MMP1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6028110-A | Succinyl hydroxamic acid, N-formyl-N-hydroxy amino carboxylic acid and succinic acid amide derivatives as metalloprotease inhibitors | BRITISH BIOTECH PHARMACEUTICALS LTD. (GB) | 2000-02-22 | — | — | US | disclosed |
| EP-0763012-B1 | SUCCINYL HYDROXAMIC ACID, N-FORMYL-N-HYDROXY AMINO CARBOXYLIC ACID AND SUCCINIC ACID AMIDE DERIVATIVES AS METALLOPROTEASE INHIBITORS | BRITISH BIOTECH PHARM (GB) | 1999-06-09 | — | — | EP | disclosed |