Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 15/20 | 0.42 |
| ▸ | MMP3 | P08254 | 10/20 | 0.42 |
| ▸ | MMP1 | P03956 | 9/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CCKBR | P32239 | 1/20 | 0.41 |
| ▸ | MMP7 | P09237 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8055024 | 0.88 | CTSK (0.44) | MMP2MMP3MMP1 | |
| SCHEMBL8053746 | 0.88 | MMP2 (0.54) | MMP2MMP3MMP1MMP7 | |
| SCHEMBL8060170 | 0.88 | MMP2 (0.54) | MMP2MMP3MMP1MMP7 | |
| SCHEMBL8057878 | 0.88 | MMP2 (0.54) | MMP2MMP3MMP1MMP7 | |
| SCHEMBL8053893 | 0.88 | MMP2 (0.54) | MMP2MMP3MMP1MMP7 | |
| SCHEMBL8777260 | 0.79 | MMP2 (0.55) | MMP2MMP3MMP1MMP7 | |
| SCHEMBL6159691 | 0.76 | CTSK (0.45) | — | |
| SCHEMBL8054968 | 0.74 | MMP2 (0.77) | MMP2MMP3MMP1MMP7 | |
| SCHEMBL5076609 | 0.73 | ALDH1A1 (0.52) | MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL5075437 | 0.73 | ALDH1A1 (0.52) | MEN1ALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6028110-A | Succinyl hydroxamic acid, N-formyl-N-hydroxy amino carboxylic acid and succinic acid amide derivatives as metalloprotease inhibitors | BRITISH BIOTECH PHARMACEUTICALS LTD. (GB) | 2000-02-22 | — | — | US | disclosed |
| EP-0763012-B1 | SUCCINYL HYDROXAMIC ACID, N-FORMYL-N-HYDROXY AMINO CARBOXYLIC ACID AND SUCCINIC ACID AMIDE DERIVATIVES AS METALLOPROTEASE INHIBITORS | BRITISH BIOTECH PHARM (GB) | 1999-06-09 | — | — | EP | disclosed |