Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8022208 | 0.90 | CES1 (0.37) | CES1L3MBTL1MEN1NPC1RAB9A | |
| SCHEMBL8056374 | 0.89 | MAPT (0.33) | MAPTTDP1 | |
| SCHEMBL8056031 | 0.88 | CES1 (0.36) | CES1L3MBTL1MEN1NPC1RAB9A | |
| SCHEMBL8043523 | 0.79 | MAPT (0.30) | MAPT | |
| SCHEMBL8023619 | 0.79 | MAPT (0.36) | L3MBTL1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL8055034 | 0.78 | KCNJ11 (0.32) | SLC6A2SLC6A4 | |
| SCHEMBL29447338 | 0.78 | ALDH1A1 (0.39) | MAPTTDP1 | |
| SCHEMBL3955072 | 0.78 | ALDH1A1 (0.39) | MAPTTDP1 | |
| SCHEMBL8029660 | 0.77 | CYP2A6 (0.42) | MAPTTDP1 | |
| SCHEMBL6420832 | 0.77 | CYP2A6 (0.36) | CES1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0704449-B1 | Process for the preparation of diphosphanes | CELANESE CHEM EUROPE GMBH (DE) | 2000-05-24 | — | — | EP | disclosed |
| US-5696296-A | Diphosphines and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-12-09 | — | — | US | disclosed |
| EP-0704449-A1 | Diphosphanes and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-04-03 | — | — | EP | disclosed |