Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HPRT1 | P00492 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
| ▸ | NQO2 | P16083 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.31 |
| ▸ | NQO1 | P15559 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8010779 | 0.88 | CYP1A2 (0.36) | CYP2A6CYP1A2HPRT1ALDH1A1HSD17B10 | |
| SCHEMBL6418430 | 0.86 | HPRT1 (0.38) | CYP2A6CYP1A2HPRT1ALDH1A1HSD17B10 | |
| SCHEMBL8022208 | 0.86 | CES1 (0.37) | CYP2A6CYP1A2HPRT1ALDH1A1HSD17B10 | |
| SCHEMBL8056031 | 0.83 | CES1 (0.36) | CYP2A6CYP1A2HPRT1ALDH1A1HSD17B10 | |
| SCHEMBL6419128 | 0.83 | CYP2A6 (0.38) | CYP2A6CYP1A2ALDH1A1HSD17B10TDP1 | |
| SCHEMBL29447338 | 0.82 | ALDH1A1 (0.39) | CYP2A6HPRT1ALDH1A1HSD17B10TDP1 | |
| SCHEMBL3955072 | 0.82 | ALDH1A1 (0.39) | CYP2A6HPRT1ALDH1A1HSD17B10TDP1 | |
| SCHEMBL8029934 | 0.81 | CYP1A2 (0.34) | CYP2A6CYP1A2ALDH1A1HSD17B10TSHR | |
| SCHEMBL6419267 | 0.81 | P2RX1 (0.40) | CYP1A2ALDH1A1TDP1CYP1B1MAPT | |
| SCHEMBL29695262 | 0.80 | ALDH1A1 (0.38) | CYP2A6HPRT1ALDH1A1HSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0653432-B1 | Process for preparing bis-(diaryl-alkyl)-phosphines and derivatives of this class of substances | CELANESE CHEM EUROPE GMBH (DE) | 2000-02-09 | — | — | EP | claimed |
| US-5600006-A | Bis(diarylalkyl)phosphines | HOECHST A.G. (DE) | 1997-02-04 | — | — | US | claimed |
| EP-0653432-A1 | Process for preparing bis-(diaryl-alkyl)-phosphines and novel derivatives of this class of substances | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-05-17 | — | — | EP | claimed |
| US-6956133-B2 | Process for hydroformylating an olefin | OXENO OLEFINCHEMIE GMBH (DE) | 2005-10-18 | — | — | US | disclosed |
| US-6924389-B2 | Method for producing diphosphines and the use thereof | OXENO OLEFINCHEMIE GMBH (DE) | 2005-08-02 | — | — | US | disclosed |
| US-20050038272-A1 | Process for preparing diphosphines | OXENO OLEFINCHEMIE GMBH (DE) | 2005-02-17 | — | — | US | disclosed |
| US-20040110979-A1 | Process for preparing diphosphines | EVONIK DEGUSSA GMBH (DE) | 2004-06-10 | — | — | US | disclosed |
| US-5600006-A | Bis(diarylalkyl)phosphines | HOECHST A.G. (DE) | 1997-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110979-A1 | Process for preparing diphosphines | CYTH2, DOHH, HRH2 | CYP2A6 258/4885CYP1A2 135/4885HPRT1 40/4885 |
| US-20050038272-A1 | Process for preparing diphosphines | HRH2, HRH3, HRH4 | CYP2A6 146/4885CYP1A2 34/4885HPRT1 152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.