Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8056031 | 0.97 | CES1 (0.36) | CES1KMT2AL3MBTL1MEN1NPC1 | |
| SCHEMBL8055037 | 0.90 | CES1 (0.32) | CES1KMT2AL3MBTL1MEN1NPC1 | |
| SCHEMBL3955072 | 0.86 | ALDH1A1 (0.39) | TDP1MAPTCYP2A6ALDH1A1TSHR | |
| SCHEMBL29447338 | 0.86 | ALDH1A1 (0.39) | TDP1MAPTCYP2A6ALDH1A1TSHR | |
| SCHEMBL6420832 | 0.86 | CYP2A6 (0.36) | CES1TDP1MAPTCYP2A6ALDH1A1 | |
| SCHEMBL8832750 | 0.85 | DRD2 (0.31) | ALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL29695262 | 0.85 | ALDH1A1 (0.38) | TDP1MAPTCYP2A6ALDH1A1TSHR | |
| SCHEMBL8023619 | 0.84 | MAPT (0.36) | KMT2AL3MBTL1MEN1NPC1RAB9A | |
| Potassium SCHEMBL29695394 | 0.83 | WDR5 (0.37) | TDP1MAPTCYP2A6ALDH1A1TSHR | |
| SCHEMBL5509956 | 0.83 | CNR2 (0.35) | L3MBTL1TDP1MAPTCYP2A6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0653432-B1 | Process for preparing bis-(diaryl-alkyl)-phosphines and derivatives of this class of substances | CELANESE CHEM EUROPE GMBH (DE) | 2000-02-09 | — | — | EP | claimed |
| US-5600006-A | Bis(diarylalkyl)phosphines | HOECHST A.G. (DE) | 1997-02-04 | — | — | US | claimed |
| EP-0653432-A1 | Process for preparing bis-(diaryl-alkyl)-phosphines and novel derivatives of this class of substances | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-05-17 | — | — | EP | claimed |
| EP-0653432-B1 | Process for preparing bis-(diaryl-alkyl)-phosphines and derivatives of this class of substances | CELANESE CHEM EUROPE GMBH (DE) | 2000-02-09 | — | — | EP | disclosed |
| US-5600006-A | Bis(diarylalkyl)phosphines | HOECHST A.G. (DE) | 1997-02-04 | — | — | US | disclosed |
| EP-0653432-A1 | Process for preparing bis-(diaryl-alkyl)-phosphines and novel derivatives of this class of substances | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-05-17 | — | — | EP | disclosed |