Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.70 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.70 |
| ▸ | PLAU | P00749 | 5/20 | 0.53 |
| ▸ | HPN | P05981 | 5/20 | 0.53 |
| ▸ | MMP2 | P08253 | 11/20 | 0.51 |
| ▸ | MMP9 | P14780 | 10/20 | 0.51 |
| ▸ | MMP8 | P22894 | 4/20 | 0.50 |
| ▸ | MMP12 | P39900 | 4/20 | 0.50 |
| ▸ | MMP14 | P50281 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MMP3 | P08254 | 2/20 | 0.48 |
| ▸ | MMP13 | P45452 | 2/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP7 | P09237 | 1/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1509767 | 0.99 | ITGB3 (0.71) | ITGB3ITGA2BPLAUHPNMMP2 | |
| SCHEMBL1509766 | 0.99 | ITGB3 (0.71) | ITGB3ITGA2BPLAUHPNMMP2 | |
| SCHEMBL9293208 | 0.99 | ITGB3 (0.71) | ITGB3ITGA2BPLAUHPNMMP2 | |
| Hydrochloric Acid SCHEMBL7362847 | 0.98 | ITGB3 (0.70) | ITGB3ITGA2BPLAUHPNMMP2 | |
| Hydrochloric Acid SCHEMBL7362845 | 0.98 | ITGB3 (0.70) | ITGB3ITGA2BPLAUHPNMMP2 | |
| Methoxymethane SCHEMBL8925022 | 0.95 | ITGB3 (0.67) | ITGB3ITGA2BPLAUHPNMMP2 | |
| SCHEMBL6347006 | 0.93 | ITGB3 (0.65) | ITGB3ITGA2BPLAUHPNMMP2 | |
| SCHEMBL1244355 | 0.91 | ITGB3 (0.60) | ITGB3ITGA2BPLAUHPNMMP2 | |
| Hydrochloric Acid SCHEMBL7319933 | 0.89 | ITGB3 (0.59) | ITGB3ITGA2BPLAUHPNMMP2 | |
| SCHEMBL3448321 | 0.88 | MMP9 (0.58) | ITGB3ITGA2BMMP2MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6113816-A | Kit for conducting an assay to detect a substance using enzymatically-induced decomposition of dioxetanes | TROPIX, INC. (US) | 2000-09-05 | — | — | US | claimed |