Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.60 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.60 |
| ▸ | PLAU | P00749 | 7/20 | 0.54 |
| ▸ | HPN | P05981 | 7/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALB | P02768 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7319933 | 0.99 | ITGB3 (0.59) | ITGB3ITGA2BPLAUHPNALDH1A1 | |
| SCHEMBL1509767 | 0.92 | ITGB3 (0.71) | ITGB3ITGA2BPLAUHPNTDP1 | |
| SCHEMBL9293208 | 0.92 | ITGB3 (0.71) | ITGB3ITGA2BPLAUHPNTDP1 | |
| SCHEMBL1509766 | 0.92 | ITGB3 (0.71) | ITGB3ITGA2BPLAUHPNTDP1 | |
| Hydrochloric Acid SCHEMBL7362847 | 0.91 | ITGB3 (0.70) | ITGB3ITGA2BPLAUHPNTDP1 | |
| Hydrochloric Acid SCHEMBL7362845 | 0.91 | ITGB3 (0.70) | ITGB3ITGA2BPLAUHPNTDP1 | |
| Ammonia Solution, Strong SCHEMBL8055739 | 0.91 | ITGB3 (0.70) | ITGB3ITGA2BPLAUHPNTDP1 | |
| Methyl P-Toluenesulfonyl-L-Argininate SCHEMBL324561 | 0.90 | ITGB3 (0.57) | ITGB3ITGA2BPLAUHPNALDH1A1 | |
| Methyl P-Toluenesulfonyl-L-Argininate SCHEMBL2853451 | 0.90 | ITGB3 (0.57) | ITGB3ITGA2BPLAUHPNALDH1A1 | |
| Methyl P-Toluenesulfonyl-L-Argininate SCHEMBL1034821 | 0.89 | ITGB3 (0.56) | ITGB3ITGA2BPLAUHPNALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7883903-B2 | Chemiluminescent substrate for use as diagnostic tool in analysis of macromolecules; substrate delivery systems comprising a conjugate a dendrimer and at least one chemiluminescent substrate; improving the machine readability, sensitivity and performance aspects of the assays | APPLIED BIOSYSTEMS, LLC | 2011-02-08 | — | — | US | claimed |
| EP-1358344-B1 | Dendritic chemiluminescent substrates | APPLERA CORP (US) | 2007-08-29 | — | — | EP | claimed |
| US-20070184491-A1 | Dendritic chemiluminescent substrates | APPLIED BIOSYSTEMS, INC. | 2007-08-09 | — | — | US | claimed |
| US-7214546-B2 | Dendritic chemiluminescent substrates | APPLERA CORPORATION (US) | 2007-05-08 | — | — | US | claimed |
| EP-1120423-B1 | Improved chemiluminescent 1,2-dioxetanes | APPLERA CORP (US) | 2007-03-14 | — | — | EP | claimed |
| EP-1120422-B1 | Improved chemiluminescent 1,2-dioxetanes | APPLERA CORP (US) | 2006-08-02 | — | — | EP | claimed |
| EP-1358344-A4 | DENDRITIC CHEMILUMINESCENT SUBSTRATES | APPLERA CORP (US) | 2004-11-03 | — | — | EP | claimed |
| EP-1358344-A2 | Dendritic chemiluminescent substrates | TROPIX, INC. (US) | 2003-11-05 | — | — | EP | claimed |
| US-20020155523-A1 | Chemiluminescent substrate for use as diagnostic tool in analysis of macromolecules | APPLIED BIOSYSTEMS, INC. | 2002-10-24 | — | — | US | claimed |
| WO-2002057745-A2 | DENDRITIC CHEMILUMINESCENT SUBSTRATES | TROPIX, INC. (US) | 2002-07-25 | — | — | WO | claimed |
| US-5582980-A | Chemiluminescent 1,2-dioxetanes | TROPIX, INC. (US) | 1996-12-10 | — | — | US | claimed |
| US-5543295-A | ENZYMATICALLY CLEAVABLE; ANALYZING | TROPIX, INC. (US) | 1996-08-06 | — | — | US | claimed |
| US-5538847-A | Chemiluminescent 1,2-dioxetanes | TROPIX, INC. (US) | 1996-07-23 | — | — | US | claimed |
| EP-0649417-A1 | IMPROVED CHEMILUMINESCENT 1,2-DIOXETANES | TROPIX, INC. (US) | 1995-04-26 | — | — | EP | claimed |
| EP-0649417-A4 | IMPROVED CHEMILUMINESCENT 1,2-DIOXETANES. | TROPIX INC (US) | 1995-02-27 | — | — | EP | claimed |
| WO-1994026726-A1 | IMPROVED CHEMILUMINESCENT 1,2-DIOXETANES | TROPIX, INC. (US) | 1994-11-24 | — | — | WO | claimed |
| US-5330900-A | Chemiluminescent 3-(substituted adamant-2'-ylidene) 1,2-dioxetanes | TROPIX, INC. (US) | 1994-07-19 | — | — | US | claimed |
| US-5326882-A | High speed bioassay | TROPIX, INC. (US) | 1994-07-05 | — | — | US | claimed |
| US-5220005-A | Reactable with enzyme to release optically detectable energy | TROPIX, INC. (US) | 1993-06-15 | — | — | US | claimed |
| US-5112960-A | Enzyme cleavable 1,2-dioxetane compound | APPLIED BIOSYSTEMS, LLC | 1992-05-12 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020155523-A1 | Chemiluminescent substrate for use as diagnostic tool in analysis of macromolecules | LPO, DCLRE1B, LIG3 | ITGB3 3465/4885ITGA2B 3441/4885PLAU 637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.