Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 6/20 | 0.44 |
| ▸ | CES2 | O00748 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.34 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19285769 | 0.93 | CES2 (0.46) | CES1CES2ALDH1A1AKR1B1TSHR | |
| SCHEMBL19285720 | 0.91 | CES2 (0.48) | CES1CES2ALDH1A1TSHRSLC22A6 | |
| SCHEMBL31187771 | 0.91 | CES2 (0.48) | CES1CES2ALDH1A1TSHRSLC22A6 | |
| SCHEMBL9331605 | 0.88 | ALDH1A1 (0.39) | CES1CES2ALDH1A1CA1TSHR | |
| SCHEMBL9331501 | 0.88 | TSHR (0.42) | ALDH1A1CA1TSHRSLC22A6 | |
| SCHEMBL2990571 | 0.86 | ALDH1A1 (0.40) | CES1CES2ALDH1A1FAAHTSHR | |
| SCHEMBL9335001 | 0.86 | ALDH1A1 (0.43) | CES1CES2ALDH1A1TSHRSLC22A6 | |
| SCHEMBL2993052 | 0.80 | TDP1 (0.33) | ALDH1A1CA1TSHR | |
| SCHEMBL14947014 | 0.80 | ALDH1A1 (0.38) | ALDH1A1TSHR | |
| SCHEMBL27546804 | 0.80 | CA1 (0.47) | CES1CES2ALDH1A1TP53CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103328603-A | Methods for treating siliciclastic hydrocarbon-bearing formations with fluorinated amine oxides | 3M INNOVATIVE PROPERTIES CO | 2013-09-25 | — | — | CN | disclosed |
| CN-1293102-C | Iron-based catalyst composition for producing syndiotactic 1, 2-polybutadiene | BRIDGESTONE CORP (JP) | 2007-01-03 | — | — | CN | disclosed |
| CN-1527844-A | Iron-based catalyst composition for the manufacture of syndiotactic 1.2-polybutadiene | ������������ʽ���� | 2004-09-08 | — | — | CN | disclosed |
| EP-0563096-B1 | NOVEL METHYLENEBISPHOSPHONIC ACID DERIVATIVES | LEIRAS OY (FI) | 2000-05-03 | — | — | EP | disclosed |
| CN-1030609-C | Methylenebisphosphonic acid derivatives | HUHTAMAEKI YHTHYMAE OY (FI) | 1996-01-03 | — | — | CN | disclosed |
| US-5438048-A | Used for treatment of disorders related to metabolism of calcium and other bivalent metals; treats bone cancer, urolithiasis, rheumatoid arthritis, bone infection and bone degradation | LEIRAS OY (FI) | 1995-08-01 | — | — | US | disclosed |
| EP-0563096-A1 | NOVEL METHYLENEBISPHOSPHONIC ACID DERIVATIVES | LEIRAS OY (FI) | 1993-10-06 | — | — | EP | disclosed |
| WO-1992011267-A1 | NOVEL METHYLENEBISPHOSPHONIC ACID DERIVATIVES | LEIRAS OY (FI) | 1992-07-09 | — | — | WO | disclosed |
| CN-1062532-A | Novel methylene-bis phosphonate derivative | HUHTAMAEKI YHTHYMAE OY (FI) | 1992-07-08 | — | — | CN | disclosed |