SCHEMBL14947014

SCHEMBL14947014

COP(=O)(OC)C(=O)CCCC(C)=O

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.38
LMNA P02545 1/20 0.37
SLC15A2 Q16348 1/20 0.37
PAOX Q6QHF9 2/20 0.37
ACHE P22303 1/20 0.37
TSHR P16473 3/20 0.36
TDP1 Q9NUW8 1/20 0.32
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9331501 0.91 TSHR (0.42) ALDH1A1LMNATSHR
SCHEMBL9331605 0.86 ALDH1A1 (0.39) ALDH1A1LMNATSHR
SCHEMBL9335001 0.84 ALDH1A1 (0.43) ALDH1A1LMNATSHRTDP1
SCHEMBL14950196 0.81 TSHR (0.62) ALDH1A1LMNATSHR
SCHEMBL8055772 0.80 CES1 (0.44) ALDH1A1TSHR
SCHEMBL19285769 0.78 CES2 (0.46) ALDH1A1TSHRTDP1
SCHEMBL8949937 0.77 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL31187771 0.77 CES2 (0.48) ALDH1A1TSHRTDP1
SCHEMBL19285720 0.77 CES2 (0.48) ALDH1A1TSHRTDP1
SCHEMBL14947005 0.75 ALDH1A1 (0.36) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230285561-A1 Targeting Microbubbles CALIFORNIA INSTITUTE OF TECHNOLOGY 2023-09-14 US disclosed
US-11642410-B2 Targeting microbubbles CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2023-05-09 US disclosed
US-20160367669-A1 TARGETING MICROBUBBLES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2016-12-22 US disclosed
US-20130123781-A1 TARGETING MICROBUBBLES CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2013-05-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130123781-A1 TARGETING MICROBUBBLES PGF, EDNRB, FLT4 ALDH1A1 4587/4885LMNA 1956/4885SLC15A2 1568/4885
US-20230285561-A1 Targeting Microbubbles PGF, EDNRB, FLT4 ALDH1A1 4587/4885LMNA 1956/4885SLC15A2 1568/4885
US-20160367669-A1 TARGETING MICROBUBBLES PGF, EDNRB, FLT4 ALDH1A1 4587/4885LMNA 1956/4885SLC15A2 1568/4885
US-11642410-B2 Targeting microbubbles PGF, EDNRB, FLT4 ALDH1A1 4587/4885LMNA 1956/4885SLC15A2 1568/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.