Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 4/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 8/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 6/20 | 0.33 |
| ▸ | GRM5 | P41594 | 5/20 | 0.33 |
| ▸ | GRM6 | O15303 | 4/20 | 0.33 |
| ▸ | GRM3 | Q14832 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | GRM8 | O00222 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | PLCB1 | Q9NQ66 | 1/20 | 0.31 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.31 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28515430 | 0.89 | GRM1 (0.35) | GRM1SLC6A12SLC6A11 | |
| SCHEMBL27547000 | 0.76 | MAPT (0.31) | — | |
| SCHEMBL14969046 | 0.73 | PLAU (0.39) | — | |
| SCHEMBL25660648 | 0.68 | GRM1 (0.62) | GRM1GRM4GRM2GRM5GRM6 | |
| SCHEMBL10577620 | 0.68 | GRM1 (0.62) | GRM1GRM4GRM2GRM5GRM6 | |
| SCHEMBL25910070 | 0.68 | GRM1 (0.42) | GRM1GRM4GRM2GRM5GRM6 | |
| SCHEMBL5522614 | 0.68 | GRM1 (0.42) | GRM1GRM4GRM2GRM5GRM6 | |
| SCHEMBL670022 | 0.68 | GRM1 (0.62) | GRM1GRM4GRM2GRM5GRM6 | |
| SCHEMBL5183321 | 0.67 | GRM1 (0.55) | GRM1GRM4GRM2GRM5GRM6 | |
| SCHEMBL5595209 | 0.67 | GRM1 (0.33) | GRM1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6034275-A | FUGICIDES; ATICHOLESTEROL AGENTS | HOFFMANN-LA ROCHE INC. (US) | 2000-03-07 | — | — | US | disclosed |