Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 14/20 | 0.38 |
| ▸ | DRD2 | P14416 | 13/20 | 0.38 |
| ▸ | HTR7 | P34969 | 13/20 | 0.38 |
| ▸ | HTR6 | P50406 | 13/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8049912 | 0.99 | HTR2A (0.37) | HTR2ADRD2HTR7HTR6HTR1A | |
| SCHEMBL8038919 | 0.87 | HTR2A (0.38) | HTR2ADRD2HTR7HTR6HTR1A | |
| SCHEMBL8056700 | 0.84 | DRD2 (0.39) | HTR2ADRD2HTR7HTR6 | |
| Hydrochloric Acid SCHEMBL8054047 | 0.83 | DRD2 (0.39) | HTR2ADRD2HTR7HTR6 | |
| SCHEMBL8050574 | 0.77 | CYP19A1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL8050310 | 0.76 | CYP19A1 (0.31) | — | |
| SCHEMBL8054066 | 0.75 | DRD2 (0.37) | HTR2ADRD2HTR7HTR1AHTR2C | |
| Hydrochloric Acid SCHEMBL8056508 | 0.75 | DRD2 (0.37) | HTR2ADRD2HTR7HTR1AHTR2C | |
| SCHEMBL8053626 | 0.74 | SLC6A2 (0.39) | HTR1A | |
| Hydrochloric Acid SCHEMBL8051780 | 0.73 | SLC6A2 (0.39) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6022880-A | Substituted pyridylamino indoles | HOECHST MARION ROUSSEL, INC. (US) | 2000-02-08 | — | — | US | disclosed |
| US-5328920-A | Alleviating memory dysfunctions | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1994-07-12 | — | — | US | disclosed |