Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8056508 | 0.99 | DRD2 (0.37) | DRD2NPC1RAB9AKCNA3L3MBTL1 | |
| SCHEMBL8051800 | 0.81 | NPC1 (0.37) | DRD2NPC1RAB9AKCNA3L3MBTL1 | |
| SCHEMBL8050574 | 0.81 | CYP19A1 (0.32) | NPSR1LMNAHTT | |
| Hydrochloric Acid SCHEMBL8050310 | 0.80 | CYP19A1 (0.31) | NPSR1LMNAHTT | |
| Fumaric Acid SCHEMBL8053540 | 0.77 | MDM2 (0.35) | DRD2NPC1RAB9AKCNA3L3MBTL1 | |
| Fumaric Acid SCHEMBL8053531 | 0.77 | MDM2 (0.35) | DRD2NPC1RAB9AKCNA3L3MBTL1 | |
| SCHEMBL8053626 | 0.76 | SLC6A2 (0.39) | LMNASMN1; SMN2POLBHTR1ADRD3 | |
| SCHEMBL8056249 | 0.75 | HTR2A (0.38) | DRD2HTR7HTR1AHTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL8051780 | 0.75 | SLC6A2 (0.39) | LMNASMN1; SMN2POLBHTR1ADRD3 | |
| Hydrochloric Acid SCHEMBL8049912 | 0.75 | HTR2A (0.37) | DRD2HTR7HTR1AHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6022880-A | Substituted pyridylamino indoles | HOECHST MARION ROUSSEL, INC. (US) | 2000-02-08 | — | — | US | disclosed |
| US-5328920-A | Alleviating memory dysfunctions | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1994-07-12 | — | — | US | disclosed |