Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8050310 | 0.99 | CYP19A1 (0.31) | CYP19A1LMNAHTTNPSR1 | |
| SCHEMBL8054066 | 0.81 | DRD2 (0.37) | LMNAHTTNPSR1 | |
| SCHEMBL8050437 | 0.80 | SLC6A3 (0.33) | CYP19A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8056508 | 0.80 | DRD2 (0.37) | LMNAHTTNPSR1 | |
| Hydrochloric Acid SCHEMBL8040242 | 0.80 | SLC6A3 (0.32) | CYP19A1MEN1KMT2A | |
| SCHEMBL8053626 | 0.78 | SLC6A2 (0.39) | LMNAKMT2A | |
| SCHEMBL8056249 | 0.77 | HTR2A (0.38) | — | |
| Hydrochloric Acid SCHEMBL8051780 | 0.77 | SLC6A2 (0.39) | LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL8049912 | 0.76 | HTR2A (0.37) | — | |
| SCHEMBL8051650 | 0.74 | PRKCI (0.32) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6022880-A | Substituted pyridylamino indoles | HOECHST MARION ROUSSEL, INC. (US) | 2000-02-08 | — | — | US | disclosed |
| US-5328920-A | Alleviating memory dysfunctions | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1994-07-12 | — | — | US | disclosed |