Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGMT | P16455 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HPD | P32754 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PPIA | P62937 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7615166 | 0.83 | MEN1 (0.44) | MGMTMEN1KMT2AMAPTHPD | |
| SCHEMBL15013285 | 0.79 | MAPT (0.55) | MGMTMEN1KMT2AMAPTHPD | |
| SCHEMBL28231949 | 0.78 | HPD (0.51) | MGMTMEN1KMT2AMAPTHPD | |
| SCHEMBL27750368 | 0.76 | RAB9A (0.45) | MGMTMEN1KMT2AMAPTHPD | |
| SCHEMBL3614237 | 0.75 | MAPT (0.49) | MGMTMEN1KMT2AMAPTHPD | |
| SCHEMBL30318890 | 0.75 | MAPT (0.46) | MGMTMEN1KMT2AMAPTHPD | |
| SCHEMBL21487362 | 0.75 | MAPT (0.46) | MGMTMEN1KMT2AMAPTHPD | |
| SCHEMBL31285352 | 0.75 | MAPT (0.46) | MGMTMEN1KMT2AMAPTHPD | |
| SCHEMBL27617230 | 0.75 | MAPT (0.42) | MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL34476061 | 0.74 | CYP19A1 (0.46) | MGMTMEN1KMT2AMAPTHPD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112745234-A | Method for preparing bimanual center medicament by using monocyclic unsaturated compound with hydroxyl connected to non-cyclic atom | 河北化工医药职业技术学院 | 2021-05-04 | — | — | CN | claimed |
| CN-112745234-A | Method for preparing bimanual center medicament by using monocyclic unsaturated compound with hydroxyl connected to non-cyclic atom | 河北化工医药职业技术学院 | 2021-05-04 | — | — | CN | disclosed |
| CN-1228448-C | Process for preparing chiral medicine intermediate (R)-2-halogen-1-(substituted phenyl) ethanol | TIANJIN NANKAI GUARD CO LTD (CN) | 2005-11-23 | — | — | CN | disclosed |
| CN-1554767-A | Process for preparing chiral medicine intermediate (R)-2-halogen-1-(substituted phenyl) ethanol | 天津南开戈德集团有限公司 | 2004-12-15 | — | — | CN | disclosed |
| CN-1083831-C | Novel tricyclic compounds and pharmaceutical compositions containing them | ASAHI CHEMICAL IND (JP) | 2002-05-01 | — | — | CN | disclosed |
| CN-1295064-A | Novel tricyclic compounds and pharmaceutical compositions containing them | ASAHI CHEMICAL IND (JP) | 2001-05-16 | — | — | CN | disclosed |
| CN-1265651-A | Novel tricyclic compound having saturated ring and pharmaceutical composition thereof | ASAHI CHEMICAL IND (JP) | 2000-09-06 | — | — | CN | disclosed |
| EP-0997458-A1 | NOVEL TRICYCLIC COMPOUNDS HAVING SATURATED RINGS AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 2000-05-03 | — | — | EP | disclosed |
| CN-1209119-A | Novel tricyclic compounds and pharmaceutical compositions containing them | ASAHI CHEMICAL IND (JP) | 1999-02-24 | — | — | CN | disclosed |